Protein Alignment Sik3 and KP78b

DIOPT Version :9

• Sequence 1: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: NP_001163587.1
• Gene: KP78b / 41361
• FlyBaseID: FBgn0026063
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 659
• Identity: 215/659 - (32%)
• Similarity: 308/659 - (46%)
• Gaps: 165/659 - (25%)

  Fly     8 GPAAAPPTSSTPQNYKVPSTSKISVDKLL------------------RVGYYELEKTIGKGNFAV 54
            ||..:..|::||     ||.:..:|....                  ..|.|::.||:||||||.
  Fly    17 GPNTSISTTATP-----PSAAAQNVGGCFGSSGGRSSPKFQSYVNGNGYGVYKIIKTLGKGNFAK 76

  Fly    55 VKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAILKSLRHPHITRLYEVMESQSMIYLVTEY 119
            ||||.::.|..:||||:||||.||.....|.:||:.|:|.|.||:|.||.:|:||:..:|||.||
  Fly    77 VKLAIHLPTGREVAIKLIDKTALNTIARQKLYREVNIMKKLNHPNIVRLLQVIESERTLYLVMEY 141

  Fly   120 APNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNIKLADFGF 184
            ...||:|::||.||||:|.:|..:|.|||||:.|||.:.:|||||||||:|||:.|.:|:|||||
  Fly   142 VSGGELFNYLVKNGRMRERDARVLFRQLVSAIEYCHSKSIVHRDLKAENLLLDQQMKLKIADFGF 206

  Fly   185 SNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDGKTILELKSR 249
            |..:|..|.|:|:||||||||||:|:|.:|.||:.|.||||||||.||.|:|||||..:.||:.|
  Fly   207 STTFEPKAPLETFCGSPPYAAPELFRGKKYSGPEVDSWSLGVVLYTLVSGSLPFDGTNLKELRDR 271

  Fly   250 VVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEWQSEMQEQERFGDMSPGSGT 314
            |:.||:|:|:::|.|||.|||..||:.|.:|.::..::..||::....:            |:|
  Fly   272 VLRGKYRVPYYVSIECESLIRKFLVLNPTQRTSLSAVMADRWINMGYEQ------------GNG- 323

  Fly   315 VSKSASTSSLGSASDSPPQLDSVVMTHMLQLPGLTADMIAQSVHEQRFDNIYAIYNLLHDKLQQR 379
                     |....:.|..|..|....:|...|.....:.||:..|:||:||..|.||
  Fly   324 ---------LRPFQEKPMDLHDVNRLSLLSNMGHKPRDVEQSLKNQKFDDIYCTYMLL------- 372

  Fly   380 RRENQRLQHHASLAYSRSRKTSITTGVVDRSEPVKQESLDRLS-PLSNANASSSALGFGWSDVAV 443
                       .:|..||...|..:|...|..|.......|:. |::..|.:.|.:.|.
  Fly   373 -----------DVAKPRSTACSEKSGSSFRETPTAMPGSSRIPVPIAAPNVTISQVTFA------ 420

  Fly   444 DLEKYGDFELECLARSNDPPVNAQHLSAHAGGGVNGANTRRHTVGPGDVAHEQALANPNVPPIDF 508
             |:|         :..|.|                 |.|....:.|       .|||. :.|:..
  Fly   421 -LDK---------STPNRP-----------------AATSIRPMAP-------RLANA-LTPLPL 450

  Fly   509 KCPPQ----CSD--------------PTQPVPYYPVNLP-------------MLQNQPLHNLTIK 542
            ..||:    ||.              |...:|...|..|             :..||.|.:.:
  Fly   451 TPPPKKYICCSASKAANPRRSEPSSIPQSAMPKKGVGSPVDVKTTLLSAQRKLAVNQKLTSAS-- 513

  Fly   543 DQHLLKPPVVMGASSFGRRASDGGANLHIYYPATGTVVGPAQGQQMDTAGYYINPNCGTDPLAVQ 607
              |.::.|:....|    :||:            .|...|...:.:|:.         :.||.|.
  Fly   514 --HQIRSPITQSPS----QASE------------CTRTPPTHFEMLDST---------STPLKVL 551

  Fly   608 ELSPLNEQS 616
            :|...|.|:
  Fly   552 KLVASNSQT 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	139/251 (55%)
		S_TKc	41..292	CDD:214567	139/250 (56%)
		UBA_SIK	335..380	CDD:270523	13/44 (30%)
KP78b	NP_001163587.1	PKc_like	63..314	CDD:304357	139/250 (56%)
		S_TKc	63..314	CDD:214567	139/250 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810