Protein Alignment Sik3 and CG4629

DIOPT Version :9

• Sequence 1: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: NP_608564.3
• Gene: CG4629 / 33284
• FlyBaseID: FBgn0031299
• Length: 570
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 162/529 - (30%)
• Similarity: 250/529 - (47%)
• Gaps: 108/529 - (20%)

  Fly     4 TPTAGPAAAPP--TSSTPQNYKVPS---------TSKISVDKLL--------RVGYYELEKTIGK 49
            |..|.|...||  |::||.....|.         |..:..|...        |:|.|.....||:
  Fly    10 TSAATPPHPPPLTTTTTPLTICQPPPPTPPYQRLTKALQCDPRCGHEVTIGRRIGLYRFCGDIGR 74

  Fly    50 GNFAVVKLATNIVTKTKVAIKII--DKTCLNEEYLNKTFREIAILKSLRHPHITRLYEVMESQSM 112
            |||:.||||.:.:|:.|||||::  |:..|:.:.|.....|||.|:.:.||:|.||:||:|:...
  Fly    75 GNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVETLGR 139

  Fly   113 IYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENVLLDKDMNI 177
            :|||||:...||:::|:...|.::|..||.:..||:.||.:.|..|.||||:|||||||..:..:
  Fly   140 VYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRL 204

  Fly   178 KLADFGFSNHYEEGAT--LKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCGALPFDG 240
            ||||||||.....||.  |.|:||||||||||:|....|.|...|:|:||::||.:|.|.:||..
  Fly   205 KLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPFRA 269

  Fly   241 KTILELKSRVVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRW---------LSEWQ 296
            .||..||:.::.|.:.:|..:|..|.:||:.:|:..|.:|.||..::..::         |.:|:
  Fly   270 PTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVTCPKLSADLMQWE 334

  Fly   297 SEMQE-----------------------QERFGDMSPGSGTVSKSASTSSLGSASDSPPQ--LDS 336
            .....                       ::|:.::      |.|.|.:.:.....:...|  |..
  Fly   335 INQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEV------VKKPAISMNTRQQDEMFVQNFLQP 393

  Fly   337 VVMTHMLQLPGLTADMIAQSVHEQRFDNIYAIYNLLHDKLQQRRRENQRLQHHASLAYSRSRKTS 401
            :.|.|.|.:|      ::..:.|.:             ..:|.:|..:|.....||   :.:.|.
  Fly   394 IEMGHELLVP------VSSQLKEPQ-------------STEQAKRPTRRYMFCGSL---KKKVTP 436

  Fly   402 ITTGVVDRSEPVKQESLDRLSPLSNANAS-SSALGFGWS-DVAVDLEKYGDFELE---CLARSND 461
            :.|      ||.||        |:|...| .||....|: :||.|...:.:::.|   |:..
  Fly   437 MET------EPEKQ--------LANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSCVML--- 484

  Fly   462 PPVNAQHLS 470
             |.|.:.||
  Fly   485 -PTNTEDLS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	110/264 (42%)
		S_TKc	41..292	CDD:214567	110/263 (42%)
		UBA_SIK	335..380	CDD:270523	6/44 (14%)
CG4629	NP_608564.3	STKc_NIM1	63..321	CDD:270977	111/257 (43%)
		S_TKc	66..321	CDD:214567	110/254 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24343
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010