Protein Alignment Sik3 and K02E10.7

DIOPT Version :9

• Sequence 1: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: NP_001360081.1
• Gene: K02E10.7 / 186892
• WormBaseID: WBGene00019321
• Length: 609
• Species: Caenorhabditis elegans
• Alignment Length: 464
• Identity: 104/464 - (22%)
• Similarity: 182/464 - (39%)
• Gaps: 98/464 - (21%)

  Fly    47 IGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAI-----------LKSLRHPHI 100
            |..|.|..|.|.|...:..:||||         || ::||.:..:           :.|:.||.|
 Worm    56 IASGRFGTVFLGTITDSMLQVAIK---------EY-HETFHDAVLTAHDEGSTLQKIISIEHPAI 110

  Fly   101 TRLYEVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLK 165
            .:.:.|...|.::|.|.|: .:..:.|.::..|:..|.:...|..|...|:.|.|.:.:.|..|.
 Worm   111 VQTFSVSHFQDIVYKVMEF-HSWTLHDDILDKGKYDESQTKLVLVQATRALEYLHAQNLCHGTLH 174

  Fly   166 AENVLLDKDMNIKLADFGFSNHYEEGATLKTW---CGSP----PYAAPEVFQGLEYDGPKSDIWS 223
            .:|:.|.::| :|::|.       |.:....|   ..:|    |:.|||:...|.....:.|:||
 Worm   175 TKNIFLQENM-VKISDI-------ESSQFLNWLPFSQTPLHILPFIAPELHNQLSEVTSECDLWS 231

  Fly   224 LGVVLYALVCGALPF---DGKTILELKSRVVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQ 285
            |||.::.:..|:.||   ...|::|.....:||.   |...|.:.:.|:..::.|.|..|.::|.
 Worm   232 LGVCIFVMATGSCPFILESRNTMMESIQAGILGS---PVLASDKIQSLVEQLIHVNPSERMSLKS 293

  Fly   286 IIKHRWLSE---WQ----------SEMQEQERF-GDMSPGSGTVSKSASTSSLGS--------AS 328
            :|:..|::.   |.          .|:...:|| ...|....||.:..|..|:.:        ||
 Worm   294 LIEDDWMTSDLVWNYFISCHEDLIRELPVVDRFIPAESLEKSTVQRDGSEISIETLDEGYKSVAS 358

  Fly   329 DSPPQLDSVVMTHMLQLPGLTADMIAQSVHEQRFDNIYAIYNLLHDKLQQRRRENQRLQHHASLA 393
            |.|.:            |.::.:   |.|..:.....|      |.|......||.|.:....:
 Worm   359 DHPEE------------PAVSGE---QQVLTEPVPKKY------HKKFAVFAMENVRKEWDNDI- 401

  Fly   394 YSRSRKTSITTG------VVDRSEPVKQESLDRLSPLSNANASSSALGF-GWSDVAVDLEKYGDF 451
             :|..|..:..|      |:...:.:...|:  .:.:..:....:...| ...|..||.: :||:
 Worm   402 -TRIEKCKLRDGSMCLRIVIPAKDEIASSSI--FNRIIKSRLGQTIKRFRSHQDTVVDSD-FGDY 462

  Fly   452 ELECLARSN 460
            .|....|.|
 Worm   463 ALMNFRREN 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	67/265 (25%)
		S_TKc	41..292	CDD:214567	67/265 (25%)
		UBA_SIK	335..380	CDD:270523	6/44 (14%)
K02E10.7	NP_001360081.1	S_TKc	52..300	CDD:214567	67/265 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0586
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810