Protein Alignment Sik3 and LOC102551633

DIOPT Version :9

• Sequence 1: NP_001188969.1
• Gene: Sik3 / 37152
• FlyBaseID: FBgn0262103
• Length: 1471
• Species: Drosophila melanogaster
• Sequence 2: XP_038936415.1
• Gene: LOC102551633 / 102551633
• RGDID: 7576862
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 523
• Identity: 148/523 - (28%)
• Similarity: 241/523 - (46%)
• Gaps: 102/523 - (19%)

  Fly    40 YYELEKTIGKGNFAVVKLATNIVTKTKVAIKIIDKTCLNEEYLNKTFREIAILKSLRHPHITRLY 104
            :|::...:|:|:|..|.||.::.|:..||||:::   :::|.::....|.|||::|.||:|.||:
  Rat    13 HYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLE---ISKETISSILSERAILETLHHPNIIRLF 74

  Fly   105 EVMESQSMIYLVTEYAPNGEIFDHLVANGRMKEPEAARVFTQLVSAVHYCHRRGVVHRDLKAENV 169
            :|:.:.|.:..|.||||.|.:|:.:...|.::|..|.::|.|.||||.|||...:||||:|.:|:
  Rat    75 QVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNI 139

  Fly   170 LLDKDMNIKLADFGFSNHYEEGATLKTWCGSPPYAAPEVFQGLEYDGPKSDIWSLGVVLYALVCG 234
            |.|.:.|.||.|||.:..:..|..||..||:..:.|||:.....|:|.|:|:|||||:||.:..|
  Rat   140 LTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTG 204

  Fly   235 ALPFDGKTILELKSRVVLGKFRIPFFMSQECEQLIRNMLVVEPDRRYTIKQIIKHRWLSEWQSEM 299
            ..||.|.|..:::.::..|.:.||.:.|.:.|.||..:|.|.|:.|.:|:.|.||.|:.:.:..:
  Rat   205 YCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNI 269

  Fly   300 QEQERFGDMSPGSGTVSKSASTSSLGSASDSPPQLDSVVMTHMLQLPGLTADMIAQSVHEQRFDN 364
            .             |::                 .....:..||...|..|:.|.:|:.::::|.
  Rat   270 P-------------TIT-----------------CPDYKIVEMLCGMGYNANKILESLQKKKYDE 304

  Fly   365 IYAIYNLLHDKLQQRRRENQRLQHHASLAYSRSRKTSITTGVVDRSEPVKQESLDRLSPLSNANA 429
            ..|.|.:|.||::      |.::|                |......||.|   ..|.|.|.|:.
  Rat   305 PMAAYLILKDKVR------QEIEH----------------GTTTSDMPVDQ---GPLPPQSPAHH 344

  Fly   430 SSSALGFGWSDVAVDLEKYGDFELECLARSNDPPVNAQHLSAHAGGGVNGANTRRHTVGPGD-VA 493
            |.|.|         .|::          |:::|.....|:..                 ||: ||
  Rat   345 SVSGL---------PLKR----------RASEPNFGLLHIWP-----------------PGEQVA 373

  Fly   494 HEQALANPNVPPID-FKCPPQCSDPTQPVPYYPVNLPMLQNQ------PLHNLTIKDQHLLKPPV 551
            ......:.::|||. :....|.|..|..:...||..|.:.|.      ||......|.....||.
  Rat   374 RHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQ 438

  Fly   552 VMG 554
            .:|
  Rat   439 RIG 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sik3	NP_001188969.1	PKc_like	40..292	CDD:304357	97/251 (39%)
		S_TKc	41..292	CDD:214567	97/250 (39%)
		UBA_SIK	335..380	CDD:270523	12/44 (27%)
LOC102551633	XP_038936415.1	STKc_AMPK-like	13..261	CDD:270905	97/250 (39%)
		UBA_MARK_Par1	275..314	CDD:270522	10/38 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910