DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gint3 and PUX2

DIOPT Version :9

Sequence 1:	NP_611356.1	Gene:	Gint3 / 37148	FlyBaseID:	FBgn0034372	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001318177.1	Gene:	PUX2 / 814694	AraportID:	AT2G01650	Length:	458	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	128/531 - (24%)
Similarity:	208/531 - (39%)	Gaps:	172/531 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KIKKFFSRKKAEAAFKLNLTGSG---MGTGHKLNSPKQETPSSSSRQKYEAYVPPKRNEISNEAR 64
            |:|.|..        |:||:.|.   .|.|..|.|      ||||.      .||. |.|.|
plant     7 KLKGFMK--------KVNLSSSSGKFKGQGRVLGS------SSSSS------APPV-NPIQN--- 47

  Fly    65 AAASAALARIDKKTSREFNTSLSAVKAQAKRELEAERRQREEAMGTPSTTSTSTSASGGDTRNLA 129
                            .||:|      ||.......:.........|  .|:|.....|.|||..
plant    48 ----------------RFNSS------QAPNPTPRPKPNPNPLPEKP--LSSSDQKISGSTRNPD 88

  Fly   130 CE------------GVF---------------FRCPLISEEILPKSVWKVRIKEFL------YQQ 161
            .:            |.|               |.||:.......:....|.::..|      ...
plant    89 HDPVRAPQDGFDPYGAFITSSNRSQNGYSLSMFECPICKNPFTSEEEVSVHVESCLGDTNGDESS 153

  Fly   162 LEADRGLTACLIIHNCNVKEK-------------ADECIATLIRYLENLIKNPEEEKFCKIRMSN 213
            .|.|         :|.|.|.:             ::..|..|:|..:|::|.||..||.|:||||
plant   154 FEKD---------NNDNDKSEMEKLVVVYLSGKPSESSIDVLLRLFKNIVKEPENAKFRKVRMSN 209

  Fly   214 KIFSEKVRYVEGALDVLQAAGFNEVQIDGEPFLLWTKEQTEKDLDLPTLVEALKSSEII------ 272
            ....|.:..|.|.:::|:..||...:.:.|   :|..      :|:|:..:::..::::
plant   210 AKIKEAIGDVAGGVELLELVGFELKEENDE---IWAV------MDVPSEEQSILINKVVGYLEKR 265

  Fly   273 ----------------PLELDRNIKVLL---PSQACRVALPDEFYRLSPEEIKKEQQLRSEAIAQ 318
                            |.::||.|:|..   .:.|.|:.:||.||.||.:|||:|..||.:.||:
plant   266 KTESSGSSAQVMEPVAPKKIDREIRVFFSVSENVASRIEVPDSFYSLSADEIKREADLRRKKIAE 330

  Fly   319 SQMLRTKAMREREEQRNLRMYRYALVRVKFPNGLFIQGTFNVYEKISDVFEFVQSCLADESLDFS 383
            ||:|..::.:|::.:...:.|:.:::||:||:|:.:||.|..:|....::|||.|.|.:.||.|.
plant   331 SQLLIPRSYKEKQAKAARKRYKRSMIRVQFPDGVVLQGVFAPWEPTFALYEFVSSALKEPSLQFE 395

  Fly   384 LVSNSDGKLGDEDLEK---------------TLYDCKLIPNTLLLFSANDTPAPLQTD---INYL 430
            |:        |..|.|               ||.|.:|:|:.|:.|      .|::||   ...|
plant   396 LL--------DPVLVKRRVIPHTPAPGQKPITLEDEELVPSALIRF------RPIETDSLVFTGL 446

  Fly   431 KEDLLMLVQAM 441
            :.:||.:.:.:
plant   447 RNELLEISEPL 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gint3	NP_611356.1	PUB_UBXD1	171..268	CDD:198418	27/109 (25%)
Gint3	NP_611356.1	UBQ	341..414	CDD:294102	27/87 (31%)
PUX2	NP_001318177.1	PUB	175..264	CDD:198416	24/97 (25%)
PUX2	NP_001318177.1	UBX_UBXN6	354..434	CDD:340536	28/93 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2699
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I1940
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006526
OrthoInspector	1	1.000	-	-		oto4072
orthoMCL	1	0.900	-	-		OOG6_106206
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.720