Protein Alignment Gint3 and Ubxn6

DIOPT Version :10

• Sequence 1: NP_611356.1
• Gene: Gint3 / 37148
• FlyBaseID: FBgn0034372
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_077752.1
• Gene: Ubxn6 / 66530
• MGIID: 1913780
• Length: 442
• Species: Mus musculus
• Alignment Length: 473
• Identity: 156/473 - (32%)
• Similarity: 252/473 - (53%)
• Gaps: 67/473 - (14%)

  Fly     4 IKKFFSRKKAEAAFKLNLTGSGMGTGHKL------NSPKQETPSSSSRQKYEAYVPPKRNEISNE 62
            :||||...||:..||      ..|.|.||      .:.|.::|..:.||       |::.. ::|
Mouse     1 MKKFFQEIKADIKFK------SAGPGQKLTDSAGEKTTKGKSPQLALRQ-------PRQGP-TDE 51

  Fly    63 ARAAASAALARIDKKTSREFN-TSLSAVKAQAKRELEAERRQREEAMGTPSTTSTSTSASGGD-- 124
            |:.||:|||||:::|..|... ||..:::.|.::||:||           :|:|.:..|.|.:
Mouse    52 AQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELQAE-----------ATSSNNPGAPGTNSV 105

  Fly   125 -------TRNLACEGVFFRCPLISEEILPKSVWKVRIKEFLYQQLEADRGLTACLIIHNCN-VKE 181
                   :.:||..||||.||| :...|.:......||:.:......|....:.:.||..| .::
Mouse   106 PEPKEEISPHLAVPGVFFICPL-TGVTLRRDQRDAHIKQAILSHFSTDPVAASIMKIHTFNRDRD 169

  Fly   182 KADECIATLIRYLENLIKNPEEEKFCKIRMSNKIFSEKVRYVEGALDVLQAAGFNEVQI-----D 241
            :....:.|:.:||:|:..:|||||:.||::.||:|.|::..:||:.:..:|.||.:|.:     :
Mouse   170 RVKLGVDTIAKYLDNIHLHPEEEKYQKIKLQNKVFQERINCLEGSHEFFEAIGFKKVTLPVPDQE 234

  Fly   242 G-EPFLLWTKEQTEKDLDLPTLVEALKSSEIIPLELDRNIKVLLPSQ-ACRVALPDEFYRLSPEE 304
            | |.|.:..::...:..:|....:.|..:|.:...|||.::|..||. |....||.:|:.|:.||
Mouse   235 GQEEFYVLGEDARAQPQNLARHKQQLLDAEPVRATLDRQLRVFRPSALASHFELPSDFFSLTAEE 299

  Fly   305 IKKEQQLRSEAIAQSQMLRTKAMREREEQRNLRMYRYALVRVKFPNGLFIQGTFNVYEKISDVFE 369
            :|:||:||:||:.:...||||||||:||||.||.|.||||||:.|:|..:||||...||:|.:|.
Mouse   300 VKREQRLRTEAVERLSSLRTKAMREKEEQRELRKYTYALVRVRLPDGCLLQGTFYAREKLSALFR 364

  Fly   370 FVQSCLADESLDFSLVSNSDGKLGDEDLEKTLYDCKLIPNTLLLFS-----------ANDTPAPL 423
            ||:..|.::.|.|.|.::...|| :|:....|.:|.|:|:.||.||           |...||.
Mouse   365 FVREALQNDWLPFELRASGGQKL-EENEALALNECGLVPSALLTFSWDASVLEDIRAAGAEPAK- 427

  Fly   424 QTDINYLKEDLLMLVQAM 441
                :.|:.:||..::.:
Mouse   428 ----SVLRPELLAAIEQL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gint3	NP_611356.1	PUB_UBXD1	171..268	CDD:198418	29/103 (28%)
		UBX_UBXN6	341..415	CDD:340536	31/73 (42%)
Ubxn6	NP_077752.1	Mediates interaction with LMAN1. /evidence=ECO:0000250|UniProtKB:Q9BZV1	1..10		4/8 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	13..111		33/122 (27%)
		VCP/p97-interacting motif (VIM). /evidence=ECO:0000250|UniProtKB:Q9BZV1	51..63		8/11 (73%)
		PUB_UBXD1	158..261	CDD:198418	28/102 (27%)
		UBX_UBXN6	336..409	CDD:340536	31/73 (42%)