Protein Alignment CG30122 and Hnrnpul2

DIOPT Version :10

• Sequence 1: NP_001163196.1
• Gene: CG30122 / 37146
• FlyBaseID: FBgn0050122
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_001292149.1
• Gene: Hnrnpul2 / 309197
• RGDID: 1562784
• Length: 745
• Species: Rattus norvegicus
• Alignment Length: 1046
• Identity: 277/1046 - (26%)
• Similarity: 398/1046 - (38%)
• Gaps: 380/1046 - (36%)

  Fly     5 KLEKMKVVDLRNELQSRGLDTKGVKAVLVERLRAYVE----------GGAGDGENAPVTPSRRQR 59
            :::::||.:||:|||.||||::|:|..|.:||:..::          ||||.|
  Rat     2 EVKRLKVTELRSELQRRGLDSRGLKMDLAQRLQEALDAEMLEDEAGVGGAGPG------------ 54

  Fly    60 RTRSMSRSPSPVQAAPVAAEPVLDTLE-EEEQPEDKTVPQPEPESEQPAAE---------PEPEQ 114
              .:....|.||.|:  ...|..|..| :||:.||:.....|.:.|.|.|:         |||.:
  Rat    55 --GACKAEPRPVAAS--GGGPGGDEEEDDEEEEEDEEALLEEEDEEPPPAQALGQAAPPPPEPPE 115

  Fly   115 SEPEEAEPAAA--VTEDTTVNQAVNEESQPEPEEFDE-KSETDDKQETIEEAVPAVVPQNEVADE 176
            :...||||.|:  ..|.|..:..||     ..||.|. |.|.|
  Rat   116 TSAMEAEPEASDIPAEATAGSGGVN-----GGEEHDNGKGEED---------------------- 153

  Fly   177 PMEEDHDAAPEEQEPTQTEEPVEEKPAESTVAEHQSNGDSQKMDVDEEDSAAPKTAEETEPAAKP 241
                    .|||:...:|  |..|.|.:..|.|...:.||:|                    :||
  Rat   154 --------GPEERSGDET--PGSEAPGDKAVEEQGDDQDSEK--------------------SKP 188

  Fly   242 EDQPPERR--------KRSHSRSKSRSRSGSRSSKHRGSVGDKRESKAAAEERTVPEDEPTIEEN 298
            .....|||        |..|.|:....|..:..|:.:.....:.|:|...|::|:
  Rat   189 AGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPPPPEEEAKDEEEDQTL---------- 243

  Fly   299 KVGLSWLDSDLHLRIDPTTFASAKPLTSEIYSLIWSGARANYGVREGKVCFEVRLSE-----ESV 358
             |.|....||||.:|....: ..:||.||.:..:|||||:.|||.:||||||.::::     |..
  Rat   244 -VNLDTYTSDLHFQISKDRY-GGQPLFSEKFPTLWSGARSTYGVTKGKVCFEAKVTQNLPMKEGC 306

  Fly   359 PENSHYFRDEPHVRGFRVGFSMPKSSLLLGEAEHSFGYCETGRKATQSEFTDYGKPYQLDDVIGC 423
            .|          |...|||:|:..|...|||.|.|:|:...|.||...:|.::|:.:..:|||||
  Rat   307 TE----------VSLLRVGWSIDFSCSQLGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGC 361

  Fly   424 YLDLESEPCTINYTLNGEDLGVAFEFEKSILGEEGALFPHIVTKGYEYLVNFSDTEQLLVNAERP 488
            :.:.|:....::::.|||||||||...|..||:. ||.||::.|.....:||...|
  Rat   362 FANFETGEVELSFSKNGEDLGVAFRISKESLGDR-ALLPHVLCKNCVIELNFGQKE--------- 416

  Fly   489 TRKRRKPRKDEDKDKDDDKDDNDGEKWKVLDEATADDDEVEKKDEDGKASSEKDEEEAEDPEKAK 553
                                                                             
  Rat   417 ----------------------------------------------------------------- 416

  Fly   554 EDEAAPKTETEAETKVEAPAEAAKPESEATEASETAETSTEKSSETAAVSNGDAAAEQANDEKAS 618
                                                                             
  Rat   417 ----------------------------------------------------------------- 416

  Fly   619 EDKKPSENNDEEDEDGPSPNKRPKTDGDSEKAESEKEKDRSQTTEDEYEDVVPEPRDTAALLEGY 683
                                                            |...|.|       |.:
  Rat   417 ------------------------------------------------EPFFPPP-------EEF 426

  Fly   684 VLIGLVPVEKLVSGPQRVGSRKECEVILLVGLPGAGKTHWAHKHVAENADKRYELIGPDAFISKM 748
            |.|..||||:.|.......:.:||||||:|||||:|||.||.|:..||.:|||.::|.:..:::|
  Rat   427 VFIHAVPVEERVRTAVPPKTIEECEVILMVGLPGSGKTQWALKYAKENPEKRYNVLGAETVLTQM 491

  Fly   749 TIDGASRKTVHKGRWDKVYEICLNSLAALEDIAMKRRRNFILDQTNVYASAQRRKMKGFNDFKRI 813
            .:.|.....:.....|.:.:.....|:.|..||.:.:|||||||.|||.|.||||:..|..|.|.
  Rat   492 RMKGLEEPEMDPKSRDLLVQQASQCLSKLVQIASRSKRNFILDQCNVYNSGQRRKLLLFKTFSRK 556

  Fly   814 AVVCIPSEDELKRRI-AEKEEKGNAFTVKESTINNLRANFTLPSLEFGWFDDINYTELTGDEAKS 877
            .||.:|:|::.|:|: ..||.:|:  .|.||.:..::|||:||. :..:.|::.|.||..:||:.
  Rat   557 VVVVVPNEEDWKKRLELRKEVEGD--DVPESIMLEMKANFSLPE-KCDYMDEVTYGELEKEEAQP 618

  Fly   878 EVKKYNEKGKKAIDAERSRDKRSRGSRDNYRRDDRN-RNRYNDDRRRDY-GGQRHESRWSDSRRG 940
            .|.||.|:.:|.:.....|..         ||::|| |||.|..|.:.| ||||
  Rat   619 IVTKYKEEARKLLPPSEKRTN---------RRNNRNKRNRQNRSRGQGYVGGQR----------- 663

  Fly   941 GGGGGYSSNSGGGGSRGYDNRRNYNSGSGGQQNWVQNSRRSGYD---DRGYGGGGSG--SRGYD- 999
                           ||||||      :.|||.|.|:..|.||.   || |.|....  ||.|:
  Rat   664 ---------------RGYDNR------AYGQQYWGQSGNRGGYRNFYDR-YRGDYERFYSRDYEY 706

  Fly  1000 NRNRGY 1005
            ||.|.|
  Rat   707 NRYRDY 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30122	NP_001163196.1	SAP	6..40	CDD:460424	16/33 (48%)
		PLN03124	8..>168	CDD:215591	54/182 (30%)
		SPRY_hnRNP	300..480	CDD:293942	69/184 (38%)
		PTZ00121	<520..>677	CDD:173412	3/156 (2%)
		AAA_33	709..855	CDD:463952	60/146 (41%)
		SF-CC1	1036..>1108	CDD:273721
Hnrnpul2	NP_001292149.1	SAP	3..37	CDD:128789	16/33 (48%)
		PRK12678	6..>210	CDD:237171	73/276 (26%)
		SPRY_hnRNP	244..415	CDD:293942	69/182 (38%)
		AAA_33	452..597	CDD:463952	60/146 (41%)