Protein Alignment CG30122 and hrpu-1

DIOPT Version :10

• Sequence 1: NP_001163196.1
• Gene: CG30122 / 37146
• FlyBaseID: FBgn0050122
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: NP_001255853.1
• Gene: hrpu-1 / 178421
• WormBaseID: WBGene00012769
• Length: 1667
• Species: Caenorhabditis elegans
• Alignment Length: 1070
• Identity: 233/1070 - (21%)
• Similarity: 366/1070 - (34%)
• Gaps: 391/1070 - (36%)

  Fly    46 DGENAP-----VTPSRRQRRTRSMSRSPSPVQAAPVAAEPVLDTLEEEEQPEDKTVPQPEPESEQ 105
            ||...|     :..|..|||.:.:..|.|...|.||...|      .|..|.... |.|.|.:.:
 Worm   602 DGIPPPPPKPLLATSDLQRRVQEIFSSESSAPAVPVVFSP------REASPPPPP-PPPRPSALK 659

  Fly   106 PAAEP-------EPEQSEPEEAEPAAAVTEDTTVNQAVNEESQPEPE---EFDEKS--------- 151
            |..||       |||:.:.::.:   .|..||.|      |.:|.|.   |.:|.|
 Worm   660 PKTEPKQVVLKQEPEEHDDDDDD---FVIRDTVV------EDEPAPRCRIEQEEASAPPAPVEPL 715

  Fly   152 ETDDKQETIEEAVPAVVPQNEVADEPMEE----------------DHDAAPE------------- 187
            |..|.|:  |::.|..|  |:|.::..:|                |.:..||
 Worm   716 EPLDPQQ--EDSAPRAV--NKVVEQRKKEALAEERRRRAMELGDGDGEYNPEDSAIGQDESEIVW 776

  Fly   188 EQEPTQT-----EEPVEEKPAESTVAEHQSNGDSQKMDVDEEDSA----APKTAEETEPAAKPED 243
            |.:|..|     ||.:||...:....:.....|.::.|.::|:.|    ||:..|..|....||:
 Worm   777 EYQPIMTRMEDEEEEMEENEGDDEDEDEMVMDDEEEDDDEDEEEATNLDAPEAPEALEAQEDPEE 841

  Fly   244 ------QPPERRKRS----HSRSKSR------------------SRSGSRSSKHRGSVGD----- 275
                  .|.|..||:    ||.:.:.                  .|:.....:.....||
 Worm   842 LNVLEQNPMELLKRALPLLHSSTVTEQPKHDYAQLELPITESLLKRTDDEQPEEVYYHGDPVPEV 906

  Fly   276 ---------------KRESKAAA---EERTVPEDEPTIEENKVGLSWLDSDLHLRIDPTTFASAK 322
                           |:|.||..   ||..||.|..|||     |.:.::|:.::.........:
 Worm   907 DENELYEIAAGIKPKKKEKKALVQIPEEERVPADSETIE-----LDYYNADILVKSAEKDIWQIE 966

  Fly   323 PLTSEIYSLIWSGARANYGVR-----EGK-----VCFEVRL-SEESVPE-NSHYFRDEPHVRGFR 375
            |...:..:|:|.|.|:|:|::     .||     :.|:::: |.:|:.. .:.:..|...|   |
 Worm   967 PFNQDGLALMWGGIRSNFGIKLPFKQTGKDASHRLAFQIQIDSYQSIQHLPTEFMADGGDV---R 1028

  Fly   376 VGFSMPK-SSLLLGEAEHSFGYCETGRKATQSEFTDYGKPYQLDDVIGCYLDLESEPCTINYTLN 439
            :|||:.. :||:|||:..|:....:|::|..:.|:|:||.:.:.||:.|..||...  ||:|.:|
 Worm  1029 IGFSLASTASLILGESPGSWCISASGKRAANNHFSDFGKLFDIGDVVTCIFDLSVG--TISYQIN 1091

  Fly   440 GEDLGVAFEFEKSILGEEG-ALFPHIVTKGYEYLVNFSDTEQLLVNAERPTRKRRKPRKDEDKDK 503
            ||::|..||   |:...|| .:||.|.||.....||..   |.|.:
 Worm  1092 GENVGSPFE---SLQFREGDVIFPTICTKNANINVNMG---QELTD------------------- 1131

  Fly   504 DDDKDDNDGEKWKVLDEATADDDEVEKKDEDGKASSEKDEEEAEDPEKAKEDEAAPKTETEAETK 568
                     ||||
 Worm  1132 ---------EKWK---------------------------------------------------- 1135

  Fly   569 VEAPAEAAKPESEATEASETAETSTEKSSETAAVSNGDAAAEQANDEKASEDKKPSENNDEEDED 633
                                                                             
 Worm  1136 ----------------------------------------------------------------- 1135

  Fly   634 GPSPNKRPKTDGDSEKAESEKEKDRSQTTEDEYEDVVPEPRDTAALLEGYVLIGLVPVEKLVSGP 698
                                                :||.||       ::.|..:....||...
 Worm  1136 ------------------------------------IPEDRD-------WMFITEMDRAHLVRSH 1157

  Fly   699 QRVGSRKECEVILLVGLPGAGKTHWAHKHVAENADKRYELIGPDAFISKMTIDGASR-KTVHKGR 762
            ....::|:|.|::.|||||.|||.|..:::||:..:.:.||..|..:..|.::|..| :.....|
 Worm  1158 TAPAAKKDCTVLMTVGLPGVGKTTWVRRYLAEHPHEHWTLISADVVMDAMKVNGVPRIRLPTLKR 1222

  Fly   763 WDKVYEICLNSLAALEDIAMKRRRNFILDQTNVYASAQRRKMKGFNDFKRIAVVCIPSEDELKRR 827
            .|.:..|...|:..|..:|.:||:|:|||.||.:|..::||:..|.:|.|..::.:|.||..::|
 Worm  1223 PDFLRGIIGKSMNRLILLAPRRRKNYILDMTNCFAEKRKRKLMAFEEFNRKCMLFVPDEDTHQKR 1287

  Fly   828 IAEKEEKGNAFTVKESTINNLRANFTLPSLEFGWFDDINYTELTGDEAKSEVKKYNEKGKKAIDA 892
            :.::|.:.|.....::.:.: :|..:||.:..|  :...........|..|...::..||.
 Worm  1288 LIKQEHEENEKLDTDAMMQH-KAAMSLPIVAEG--EPCEELIFIDPPAGCEQIAFDRVGKM---- 1345

  Fly   893 ERSRDKRSRGSRDNYRRDDRNRNRYNDDRRRDYGGQRHESRWSDSRRGGGGGGYSSNSGGGGSRG 957
                         ||   |.........|||..||..:.....|  ||||||.|..    ||...
 Worm  1346 -------------NY---DCRSWLVIPGRRRGGGGYNNHHNRGD--RGGGGGNYHH----GGYHQ 1388

  Fly   958 YDNRRNYNSGSGGQQNWVQNSRRSGYDDRG 987
            |:........|||.|          |..||
 Worm  1389 YNRPSTSGPPSGGAQ----------YSPRG 1408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30122	NP_001163196.1	SAP	6..40	CDD:460424
		PLN03124	8..>168	CDD:215591	39/145 (27%)
		SPRY_hnRNP	300..480	CDD:293942	56/193 (29%)
		PTZ00121	<520..>677	CDD:173412	4/156 (3%)
		AAA_33	709..855	CDD:463952	45/146 (31%)
		SF-CC1	1036..>1108	CDD:273721
hrpu-1	NP_001255853.1	SAP	18..52	CDD:128789
		PTZ00121	<151..440	CDD:173412
		SPRY	946..1128	CDD:470632	56/192 (29%)
		AAA_33	1168..1314	CDD:463952	45/146 (31%)