Protein Alignment CG30122 and Hnrnpu

DIOPT Version :9

• Sequence 1: NP_001163196.1
• Gene: CG30122 / 37146
• FlyBaseID: FBgn0050122
• Length: 1272
• Species: Drosophila melanogaster
• Sequence 2: XP_038946213.1
• Gene: Hnrnpu / 117280
• RGDID: 620372
• Length: 803
• Species: Rattus norvegicus
• Alignment Length: 1078
• Identity: 273/1078 - (25%)
• Similarity: 429/1078 - (39%)
• Gaps: 324/1078 - (30%)

  Fly     6 LEKMKVVDLRNELQSRGLDTKGVKAVLVERLRAYVEGGAGDGENAPVTPSRRQRRTRSMSRSPSP 70
            ::|:||.:|:.||:.|.|..||:||.|::||:|.::..|| |..|             |......
  Rat     8 VKKLKVSELKEELKKRRLSDKGLKADLMDRLQAALDNEAG-GRPA-------------MEPGNGS 58

  Fly    71 VQAAPVAAEPVLDTLEEEEQPEDKTVPQPEPESEQPAAEPEPEQSEPEEAEPAAAVTEDTTVNQA 135
            :.....||......||:|     ......:.|.|:..|..:.:|.|..|...||...:...:.:
  Rat    59 LDLGGDAAGRSGAGLEQE-----AAAGAEDDEEEEGIAALDGDQMELGEENGAAGAADAGAMEE- 117

  Fly   136 VNEESQPEPEEFDEKSETDDKQETIEEAVPAVVPQNEVADEPMEEDHDAAPEEQEPTQTEEPVEE 200
              ||:..|.|..|                          |:..:|..|...:|:|....|....|
  Rat   118 --EEAASEDENGD--------------------------DQGFQEGEDELGDEEEGAGDENGHGE 154

  Fly   201 KPAESTVAEHQSNGDSQKMDVDEEDSAAPKTAEETE--------PAAKPEDQPPERRKRSHSRSK 257
            :.::...|..|:   ||:....:|  ||.|::..|.        |.|:...|......::..::.
  Rat   155 QQSQPPAAAQQA---SQQRGPGKE--AAGKSSGPTSLFAVTVAPPGARQGQQQAGGDGKTEQKAG 214

  Fly   258 SRSRSGSRSSKHRGS-----VGDKRESKAAAEERTVPEDEPTIEENKVGLSWLDSDLHLRIDPTT 317
            .:.|...|..:..|.     :.:.:.|:|.:.:..|.|::...::..|.|...:.|||.:|....
  Rat   215 DKKRGVKRPREDHGRGYFEYIEENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYNCDLHFKISRDR 279

  Fly   318 FASAKPLTSEIYSLIWSGARANYGVREGKVCFEVRLSEESVPENSHYFRDEPHVRGFRVGFSMPK 382
            . ||..||.|.::.:|:|.||:|||.:||||||::::|: :|.. |.:..:..:...|:|:|:..
  Rat   280 L-SASSLTMESFAFLWAGGRASYGVSKGKVCFEMKVTEK-IPVR-HLYTKDIDIHEVRIGWSLTT 341

  Fly   383 SSLLLGEAEHSFGYCETGRKATQSEFTDYGKPYQLDDVIGCYLDLESEPCTINYTLNGEDLGVAF 447
            |.:||||.|.|:||...|.|....|..|||:.:..:|||.|:.:.|::...::|..||:||||||
  Rat   342 SGMLLGEEEFSYGYSLKGIKTCNCETEDYGEKFDENDVITCFANFETDEVELSYAKNGQDLGVAF 406

  Fly   448 EFEKSILGEEGALFPHIVTKGYEYLVNFSDTEQLLVNAERPTRKRRKPRKDEDKDKDDDKDDNDG 512
            :..|.:|.:. .||||::........||                                    |
  Rat   407 KISKEVLADR-PLFPHVLCHNCAVEFNF------------------------------------G 434

  Fly   513 EKWKVLDEATADDDEVEKKDEDGKASSEKDEEEAEDPEKAKEDEAAPKTETEAETKVEAPAEAAK 577
            :|
  Rat   435 QK--------------------------------------------------------------- 436

  Fly   578 PESEATEASETAETSTEKSSETAAVSNGDAAAEQANDEKASEDKKPSENNDEEDEDGPSPNKRPK 642
                                                       :||
  Rat   437 -------------------------------------------EKP------------------- 439

  Fly   643 TDGDSEKAESEKEKDRSQTTEDEYEDVVPEPRDTAALLEGYVLIGLVPVEKLVSGPQRVGSRKEC 707
                                      ..|.|.|.       ..|..||:|..|.||:....:|:|
  Rat   440 --------------------------YFPIPEDC-------TFIQNVPLEDRVRGPKGPEEKKDC 471

  Fly   708 EVILLVGLPGAGKTHWAHKHVAENADKRYELIGPDAFISKMTIDGASRKTVHKGRWDKVYEICLN 772
            ||::::||||||||.|..||.|||..| |.::|.:..:.||.:.|..::....|:.:.:.:....
  Rat   472 EVVMMIGLPGAGKTTWVTKHAAENPGK-YNILGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQ 535

  Fly   773 SLAALEDIAMKRRRNFILDQTNVYASAQRRKMKGFNDFKRIAVVCIPSEDELKRRIAEKEE-KGN 836
            .|....:||.:::||||||||||.|:||||||..|..|:|.|||..|.:::.|:|..:|.| :|.
  Rat   536 CLGKFIEIAARKKRNFILDQTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGK 600

  Fly   837 AFTVKESTINNLRANFTLPSLEFGWFDDINYTELTGDEAKSEVKKYNEKGKKAIDAERSRDKRSR 901
              .:.|..:..::.|||||.:. ..||:|.|.||..:||:..:::|.|:.|||:..|:   |::.
  Rat   601 --DLPEHAVLKMKGNFTLPEVA-ECFDEITYVELQKEEAQKLLEQYKEESKKALPPEK---KQNT 659

  Fly   902 GSRDNYRRDDRNRNRYNDDRRRDYGGQRHESRWSDSRRGGGGGGYSSNSGG--GGSRGYDNRRNY 964
            ||:.:      |:|:...::....||.|            |.||::...|.  ||:.|  ||..|
  Rat   660 GSKKS------NKNKSGKNQFNRGGGHR------------GRGGFNMRGGNFRGGAPG--NRGGY 704

  Fly   965 NSGSGGQQNWVQNSRRSGYDDRGYGGGGSGSRGYDNRNRGYAGG---SGGGGGGGGGGGGGGGQQ 1026
            |             ||.....|| ||||||..||.     |..|   .|.||....|....||..
  Rat   705 N-------------RRGNMPQRG-GGGGSGGIGYP-----YPRGPVFPGRGGYSNRGNYNRGGMP 750

  Fly  1027 NWMQNNRRSGYDD--RGYGSSRDYRDRDRGNDRSRMGS 1062
            |      |..|:.  ||.|::|.|:::.:|.::.:.||
  Rat   751 N------RGNYNQNFRGRGNNRGYKNQSQGYNQWQQGS 782

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30122	NP_001163196.1	SAP	6..40	CDD:280251	16/33 (48%)
		SPRY_hnRNP	300..480	CDD:293942	67/179 (37%)
		PHA02664	<529..659	CDD:177447	2/129 (2%)
		AAA_33	709..855	CDD:290396	58/146 (40%)
		NK	709..>836	CDD:302627	53/127 (42%)
		DUF1777	1033..>1104	CDD:285811	10/32 (31%)
Hnrnpu	XP_038946213.1	SAP	8..42	CDD:128789	16/33 (48%)
		SPRY_hnRNP	262..437	CDD:293942	69/320 (22%)
		AAA_33	473..617	CDD:404546	58/146 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I4973
eggNOG	1	0.900	-	-		E1_KOG2242
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2064
OMA	1	1.010	-	-		QHG47565
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001523
OrthoInspector	1	1.000	-	-		otm45295
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12381
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X963
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	11.020