DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and Fkbp11

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_077131.2	Gene:	Fkbp11 / 66120	MGIID:	1913370	Length:	201	Species:	Mus musculus

Alignment Length:	186	Identity:	40/186 - (21%)
Similarity:	71/186 - (38%)	Gaps:	49/186 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 EEDAEEECDILGNKQLIKRTIKKAPQDSFRRPIRGELVTVNFTGKLDNGTVVENELN---FQCHV 112
            |...|.|..:   :.|...|:.:.|:........|:.:.:::||.|.:|.:::..|.   ....:
Mouse    26 EAGPETESPV---RTLQVETLVQPPESCTESAAIGDTLHIHYTGSLVDGRIIDTSLTRDPLVIEL 87

  Fly   113 GDYEVIQGLDMVLPMLQVGEVSQVSVDSRFGYGSLGLKKEGESEYLVPPDAHLTYEIELLDIKYE 177
            |..:||.||:..|..:.|||..:..:.|...||..|....      :|.||.:.|::||:.:
Mouse    88 GQKQVIPGLEQSLLDMCVGEKRRAVIPSHLAYGKRGYPPS------IPADAVVQYDVELIAL--- 143

  Fly   178 EFADLKSFEILRKYGTRKKERANFFYKRSEFTTAI---------------HLYRRA 218
                               .|||::.|..:....:               ||||:|
Mouse   144 -------------------IRANYWQKLLKSILPLVGIAMVPALLGLIGYHLYRKA 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	24/94 (26%)
		TPR_11	196..284	CDD:290150	9/38 (24%)
		TPR repeat	196..220	CDD:276809	9/38 (24%)
		TPR repeat	252..282	CDD:276809
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
Fkbp11	NP_077131.2	FKBP_C	50..141	CDD:278674	24/96 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810