DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and fkbp14

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001003471.1	Gene:	fkbp14 / 445077	ZFINID:	ZDB-GENE-040801-210	Length:	211	Species:	Danio rerio

Alignment Length:	196	Identity:	47/196 - (23%)
Similarity:	83/196 - (42%)	Gaps:	44/196 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 RRPIRGELVTVNFTGKLD-NGTVVENELNFQCHVGD----------YEVIQGLDMVLPMLQVGEV 133
            |:...|:::.|::.|.|: |||:..:..    |.||          .|||:|.|..|..:..||.
Zfish    40 RKSKYGDILLVHYDGFLESNGTMFHSSR----HQGDKNPVWFTLGIREVIKGWDKGLQNMCAGEK 100

  Fly   134 SQVSVDSRFGYGSLGLKKEGESEYLVPPDAHLTYEIELLDIK-----YEEFADLKSFEILRKYGT 193
            .::::.....||     |||:.:  :||::.|.::||:::|:     :|.|.::...:..:....
Zfish   101 RKLTIPPALAYG-----KEGKGK--IPPESTLIFDIEIIEIRNGPRSHESFQEMDLNDDWKLSKA 158

  Fly   194 RKKERANFFYKRSEFTTAIHLYRRALDFLDNRDGDPDSEFDKEDL-ELSNSDTQTLLEDRLIVYN 257
            ..||     |.|.||..  |.|..         .|...|...||: :..:.|....:..|...|.
Zfish   159 EVKE-----YLRKEFEK--HGYAA---------NDTHHEVMVEDIFQKEDEDKDGFISSREFTYQ 207

  Fly   258 N 258
            :
Zfish   208 H 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	29/102 (28%)
		TPR_11	196..284	CDD:290150	15/64 (23%)
		TPR repeat	196..220	CDD:276809	8/23 (35%)
		TPR repeat	252..282	CDD:276809	2/7 (29%)
		TPR_11	255..318	CDD:290150	1/4 (25%)
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
fkbp14	NP_001003471.1	FKBP_C	38..132	CDD:278674	29/102 (28%)
		EF-hand_7	141..204	CDD:290234	16/78 (21%)
		EFh	142..204	CDD:298682	16/77 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900