DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and Fkbp39

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_524364.2	Gene:	Fkbp39 / 41860	FlyBaseID:	FBgn0013269	Length:	357	Species:	Drosophila melanogaster

Alignment Length:	202	Identity:	39/202 - (19%)
Similarity:	83/202 - (41%)	Gaps:	43/202 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DTEKSSSSSFEDLTNAEDTKDIRKVAAEEAASGDGAPPASVSGDG-----------QKAEEEDAE 55
            |.|:|.....:|..::|..::..|....:.:.|..|..:....:|           :|.|:.:|:
  Fly   163 DNEESGEEDEQDSDDSEAEEEQPKAKVAKLSPGASAKKSGKEQNGVAKKEEAKQQQKKKEKPEAK 227

  Fly    56 EE-----------------CDILGNKQLIKRTIKKAPQDSFRRPIRGELVTVNFTGKLDNGTVVE 103
            :|                 ..|.|..:::.:.:.|..:..     :|:.|:|.:.|:|.:.....
  Fly   228 KEQPKAKEPAKQQPASKDPRTITGGVKIVDQVVGKGEEAK-----QGKRVSVYYIGRLQSNNKTF 287

  Fly   104 NEL----NFQCHVGDYEVIQGLDMVLPMLQVGEVSQVSVDSRFGYGSLGLKKEGESEYLVPPDAH 164
            :.|    .|:..:|..|||:|.|:.:..::||....::......||:.|...:      :.|::.
  Fly   288 DSLLKGKPFKFALGGGEVIKGWDVGVAGMKVGGKRVITCPPHMAYGARGAPPK------IGPNST 346

  Fly   165 LTYEIEL 171
            |.:|:||
  Fly   347 LVFEVEL 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	23/96 (24%)
		TPR_11	196..284	CDD:290150
		TPR repeat	196..220	CDD:276809
		TPR repeat	252..282	CDD:276809
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
Fkbp39	NP_524364.2	FKBP_C	262..354	CDD:278674	24/103 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830