DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and Fkbp14

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001013228.1	Gene:	Fkbp14 / 362366	RGDID:	1311705	Length:	211	Species:	Rattus norvegicus

Alignment Length:	201	Identity:	45/201 - (22%)
Similarity:	84/201 - (41%)	Gaps:	57/201 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 IKRTIKKAPQDSFRRPIRGELVTVNFTGKLDNGTVVENELNFQCH-----------VGDYEVIQG 120
            :|..:.:.|....|:...|:|:.|::.|.|:.    :..|....|           :|..||::|
  Rat    27 VKIEVLQKPFICHRKTKGGDLMLVHYEGYLEK----DGSLFHSTHKHNNGQPVWFTLGILEVLKG 87

  Fly   121 LDMVLPMLQVGEVSQVSVDSRFGYGSLGLKKEGESEYLVPPDAHLTYEIELLDIK-----YEEFA 180
            .|..|..:.|||..::::....|||     |||:.:  :||::.|.:.|:||:|:     :|.|.
  Rat    88 WDQGLKGMCVGEKRKLTIPPALGYG-----KEGKGK--IPPESTLIFNIDLLEIRNGPRSHESFQ 145

  Fly   181 DLKSFEILRKYGTRKKERANFFYKRSEFTTAIHLYRRALDFLDNRDGDPDSEFDKEDLELSNSDT 245
            ::.               .|..:|.|:....::|               .:||:|....::.|..
  Rat   146 EMD---------------LNDDWKLSKHEVKVYL---------------QNEFEKHGAVVNESHH 180

  Fly   246 QTLLED 251
            ..|:||
  Rat   181 DALVED 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	27/102 (26%)
		TPR_11	196..284	CDD:290150	11/56 (20%)
		TPR repeat	196..220	CDD:276809	4/23 (17%)
		TPR repeat	252..282	CDD:276809	45/201 (22%)
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
Fkbp14	NP_001013228.1	FKBP_C	38..132	CDD:395196	27/104 (26%)
Fkbp14	NP_001013228.1	EF-hand_7	141..204	CDD:404394	13/76 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900