DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and fkbp10b

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001122138.1	Gene:	fkbp10b / 324381	ZFINID:	ZDB-GENE-030131-3101	Length:	614	Species:	Danio rerio

Alignment Length:	170	Identity:	38/170 - (22%)
Similarity:	70/170 - (41%)	Gaps:	22/170 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VAAEEAASGDGAPP-ASVSGDGQKAEEEDAEEECDILGNKQLIKRTIKKAPQDSFRRPIRGELVT 89
            :|..|...|.|.|| |||.   .....||.....|     .:|..|: |.|:...|:.:.|:.:.
Zfish   267 LAFGEQGYGTGIPPHASVE---YHILLEDLHNPKD-----DIIVETL-KLPEPCARKSVAGDFIR 322

  Fly    90 VNFTGKLDNGTVVENEL----NFQCHVGDYEVIQGLDMVLPMLQVGEVSQVSVDSRFGYGSLGLK 150
            .::.....||.:.::..    .:..::|...:|.|:|..|..:..||..::.:.....||..|..
Zfish   323 YHYNASFLNGIMFDSSYQQNQTYNTYIGMGYMIAGIDKGLQGVCAGEWRRIILPPHLAYGQQGAG 387

  Fly   151 KEGESEYLVPPDAHLTYEIELLDIKYEEFADLKSFEILRK 190
            |:      :|..|.|.::|.::|  :....|....::|.:
Zfish   388 KD------IPGSAVLVFDIHVID--FHNIKDPVQVDVLHR 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	19/95 (20%)
		TPR_11	196..284	CDD:290150
		TPR repeat	196..220	CDD:276809
		TPR repeat	252..282	CDD:276809
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
fkbp10b	NP_001122138.1	FKBP_C	87..179	CDD:278674
		FKBP_C	199..290	CDD:278674	9/25 (36%)
		FKBP_C	311..403	CDD:278674	19/97 (20%)
		FKBP_C	423..514	CDD:278674
		EF-hand_7	537..599	CDD:290234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810