DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and Fkbp9

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001007647.1	Gene:	Fkbp9 / 297123	RGDID:	1549757	Length:	570	Species:	Rattus norvegicus

Alignment Length:	228	Identity:	48/228 - (21%)
Similarity:	86/228 - (37%)	Gaps:	80/228 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 ECDILGNKQLIKRTIKKAPQDSFRRPIRGELVTVNFTGKLDNGTVVENELN----FQCHVGDYEV 117
            :|.:|..|                    |:.:..::...|.:||::::..|    :...:|..:|
  Rat   381 DCSVLSKK--------------------GDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGFGQV 425

  Fly   118 IQGLDMVLPMLQVGEVSQVSVDSRFGYGSLGLKKEGESEYLVPPDAHLTYEIELLDI-------- 174
            :.|:||.|..:.|||...|.:....|||..|:  :||    ||..|.|.::||||::
  Rat   426 VLGMDMGLREMCVGEKRTVIIPPHLGYGEAGV--DGE----VPGSAVLVFDIELLELVSGLPEGY 484

  Fly   175 -----------KYEEFADLKSFEILRKYGTRKKERANFFYKRSEFTTAIHLY------RRALDF- 221
                       .:||.....:.|:|.:                ||:..||..      :.|..|
  Rat   485 MFIWNGEVSPNLFEEIDKDGNGEVLLE----------------EFSEYIHAQVASGKGKLAPGFN 533

  Fly   222 --------LDNRDGDPDSEFDKEDLELSNSDTQ 246
                    ..|:|.:.|.:...|:.:|.:.:|:
  Rat   534 AEMIVKNMFTNQDRNGDGKVTAEEFKLKDQETK 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	27/95 (28%)
		TPR_11	196..284	CDD:290150	12/66 (18%)
		TPR repeat	196..220	CDD:276809	5/29 (17%)
		TPR repeat	252..282	CDD:276809
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
Fkbp9	NP_001007647.1	FKBP_C	47..139	CDD:278674
		FKBP_C	159..251	CDD:278674
		FKBP_C	271..362	CDD:278674
		FKBP_C	382..474	CDD:278674	30/117 (26%)
		EF-hand_7	495..559	CDD:290234	14/79 (18%)
		EFh	497..558	CDD:238008	14/76 (18%)
		Prevents secretion from ER. /evidence=ECO:0000255\|PROSITE-ProRule:PRU10138	567..570		48/228 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810