DRSC/TRiP Functional Genomics Resources

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Protein Alignment zda and Fkbp4

DIOPT Version :9

Sequence 1:NP_001286579.1 Gene:zda / 37144 FlyBaseID:FBgn0034368 Length:397 Species:Drosophila melanogaster
Sequence 2:NP_001178792.1 Gene:Fkbp4 / 260321 RGDID:628729 Length:458 Species:Rattus norvegicus


Alignment Length:354 Identity:94/354 - (26%)
Similarity:157/354 - (44%) Gaps:57/354 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 EEAASGDGAPP-----ASVSGDGQKAE--EEDAEEECDILGNKQLIKRTIKKAPQDSFRRPIRGE 86
            |.|....|:||     |::..:.:..|  .||..|:.|  |.  :|:|.  :...:.:.||..|.
  Rat   110 EYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEDED--GG--IIRRI--RTRGEGYARPNDGA 168

  Fly    87 LVTVNFTGKLDNGTVVENELNFQCHVGDYEVIQ---GLDMVLPMLQVGEVSQVSVDSRFGYGSLG 148
            :|.|...|..::....:.||.|:  ||:.|.:.   ||:..:..::.||.|.|.:...:.:||: 
  Rat   169 MVEVALEGYYNDRLFDQRELCFE--VGEGESLDLPCGLEEAIQRMEKGEHSIVYLKPSYAFGSV- 230

  Fly   149 LKKEGESEYLVPPDAHLTYEIELLDIKYEEFADLKSFEILR-----------KYGTRKKERANFF 202
                |:..:.:||.|.|.||:.           |||||..:           :.....|||...:
  Rat   231 ----GKERFQIPPHAELRYEVH-----------LKSFEKAKASWEMNSEEKLEQSNIVKERGTVY 280

  Fly   203 YKRSEFTTAIHLYRRALDFLDNRDGDPDSEFDKEDLELSNSDTQTLLEDRLIVYNNLAMTQIKIA 267
            :|..::..|:..|::.:.:|:.     :|.|..|::       |.:...||..:.||||..:|:.
  Rat   281 FKEGKYKQALLQYKKIVSWLEY-----ESSFSGEEM-------QKVHALRLASHLNLAMCHLKLQ 333

  Fly   268 AYDAALQSVEHVLRCQPNNSKALYRKGRILEGKADTQGAIKLLQKVATLEPENRAVQSDLARLFI 332
            |:.||::|....|....||.|.|:|:|.......|...|....|||..|.|.|:|.::.||....
  Rat   334 AFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFDLARADFQKVLQLYPSNKAAKTQLAVCQQ 398

  Fly   333 KARREEHNEKEMYQKMLGQAKKMEQNTAT 361
            :.||:...||::|..|..:..:.|....|
  Rat   399 RTRRQLAREKKLYANMFERLAEEEHKAKT 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
zdaNP_001286579.1 FKBP_C 80..172 CDD:278674 27/94 (29%)
TPR_11 196..284 CDD:290150 23/87 (26%)
TPR repeat 196..220 CDD:276809 6/23 (26%)
TPR repeat 252..282 CDD:276809 12/29 (41%)
TPR_11 255..318 CDD:290150 22/62 (35%)
TPR repeat 287..313 CDD:276809 7/25 (28%)
TPR repeat 321..349 CDD:276809 8/27 (30%)
Fkbp4NP_001178792.1 FKBP_C 43..134 CDD:278674 6/23 (26%)
Interaction with tubulin 267..400 40/144 (28%)
TPR_11 274..349 CDD:290150 23/86 (27%)
TPR repeat 274..301 CDD:276809 6/26 (23%)
TPR repeat 306..348 CDD:276809 15/48 (31%)
TPR_1 321..352 CDD:278916 10/30 (33%)
TPR_11 322..384 CDD:290150 22/61 (36%)
TPR repeat 353..381 CDD:276809 9/27 (33%)
TPR_2 354..386 CDD:285020 11/31 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 423..458 1/5 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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