DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and wis2

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_594787.1	Gene:	wis2 / 2542541	PomBaseID:	SPAC1B3.03c	Length:	356	Species:	Schizosaccharomyces pombe

Alignment Length:	349	Identity:	73/349 - (20%)
Similarity:	125/349 - (35%)	Gaps:	101/349 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GDGAPPASVSGDGQKAEEEDAEEECDILGNKQLIKRTIKKAPQDSFRRPIRGELVTVNFTGKLDN 98
            |:|....|:.  |:|.|:|:.|.:.|    |..:.......|..:..:.....:.|.:..||
pombe    73 GNGTGGESIY--GEKFEDENFELKHD----KPFLLSMANAGPNTNGSQFFITTVPTPHLDGK--- 128

  Fly    99 GTVVENELNFQCHVGDYEVIQGL--------------DMVLPML--QVGEVSQVSVDSRFGYGSL 147
                        ||...:||||.              |.|:|::  :.|..::..:::
pombe   129 ------------HVVFGKVIQGKSTVRTIENLETKNDDPVVPVVIEECGTCTKDQIEA------- 174

  Fly   148 GLKKEGESEYLVPPDAHLTYEIELLDIKYEEFAD----LKSFEILRKYGTRKKERANFFYKRSEF 208
                         |...:|.:      ..|||.|    .||...:.|..:..|..||..:.:...
pombe   175 -------------PKPDVTGD------SLEEFPDDYEGDKSETAIFKIASDLKGIANKQFAQQNL 220

  Fly   209 TTAIHLYRRALDFL-----DNRDGDPDSEFDKEDLELSNSDTQTLLEDRLIVYNNLAMTQIKIAA 268
            .||:..:::||.:|     .|.|.....:|.||...|           |..:|.|||:..:|...
pombe   221 DTAVAKWQKALRYLMEYPVPNDDSKESPDFWKEYNAL-----------RYSIYANLALVALKQNK 274

  Fly   269 YDAALQSVEHVLRCQPNNS------KALYRKGRILEGKADTQGAIKLL---QKVATLEPENRAVQ 324
            ...|:::...|:  :.:||      ||.||.|       ..||.:|..   :|.......:.|:.
pombe   275 PQEAIRNANIVI--EASNSTELEKQKAYYRLG-------CAQGLLKNFEESEKALAKAGNDPAIS 330

  Fly   325 SDLARLFIKARREEHNEKEMYQKM 348
            ..||.:..|.:..:..:::.|.||
pombe   331 KKLAEIRQKKKDYKKRQQKAYAKM 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	15/107 (14%)
		TPR_11	196..284	CDD:290150	22/92 (24%)
		TPR repeat	196..220	CDD:276809	6/23 (26%)
		TPR repeat	252..282	CDD:276809	8/29 (28%)
		TPR_11	255..318	CDD:290150	18/71 (25%)
		TPR repeat	287..313	CDD:276809	9/34 (26%)
		TPR repeat	321..349	CDD:276809	7/28 (25%)
wis2	NP_594787.1	cyclophilin	6..165	CDD:294131	23/112 (21%)
		TPR_11	204..287	CDD:290150	22/95 (23%)
		TPR repeat	204..253	CDD:276809	11/48 (23%)
		TPR repeat	258..288	CDD:276809	8/31 (26%)
		TPR_11	261..323	CDD:290150	18/70 (26%)
		TPR repeat	293..323	CDD:276809	9/36 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000