DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and fkb-5

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001367683.1	Gene:	fkb-5 / 171974	WormBaseID:	WBGene00001430	Length:	300	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	39/152 - (25%)
Similarity:	67/152 - (44%)	Gaps:	31/152 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GDGQKAEEEDAEEECDIL--------------GNKQ------LIKRTIKKAPQDSFRRPIRGELV 88
            |.|.|..|.|..:|...|              |.|.      :|::| .|..:|..::...|:.:
Worm   147 GFGDKGRERDNIKEDQTLYYTVQLVDLFRAVPGEKWTTDEGIVIEQT-HKIDEDKCKKSKSGDTI 210

  Fly    89 TVNFTGKLDNGTVVENELN----FQCHVGDYEVIQGLDMVLPMLQVGEVSQVSVDSRFGYGSLGL 149
            ...:...|::||.|::..:    |...:.:.|||:|:|:.:..:..||..||.:.|.||||.
Worm   211 HQQYVLHLEDGTFVDSSFSRNAPFIFKLNNNEVIKGMDIAMTGMCEGERRQVVIPSDFGYGD--- 272

  Fly   150 KKEGESEYLVPPDAHLTYEIEL 171
              :|.:. .:|..|.|.::|.|
Worm   273 --DGRAP-AIPGKARLYFDITL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	26/96 (27%)
		TPR_11	196..284	CDD:290150
		TPR repeat	196..220	CDD:276809
		TPR repeat	252..282	CDD:276809
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
fkb-5	NP_001367683.1	FKBP_C	79..171	CDD:395196	7/23 (30%)
fkb-5	NP_001367683.1	FKBP_C	202..291	CDD:395196	25/94 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160763
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840