DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment zda and fkbp9

DIOPT Version :9

Sequence 1:	NP_001286579.1	Gene:	zda / 37144	FlyBaseID:	FBgn0034368	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001123385.1	Gene:	fkbp9 / 100125793	XenbaseID:	XB-GENE-1019523	Length:	585	Species:	Xenopus tropicalis

Alignment Length:	206	Identity:	41/206 - (19%)
Similarity:	83/206 - (40%)	Gaps:	60/206 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RGELVTVNFTGKLDNGTVVENE----LNFQCHVGDYEVIQGLDMVLPMLQVGEVSQVSVDSRFGY 144
            :|:.:..::...|.:|||:::.    ..:...:|..:|:.|:|:.|..:.:||...:.:....||
Frog   401 KGDYLKYHYNATLMDGTVLDSTHQYGKTYNIVLGSGQVVMGMDIGLQDMCIGEKRNIVIPPHLGY 465

  Fly   145 GSLGLKKEGESEYLVPPDAHLTYEIELLDI-------------------KYEEFADLKSFEILRK 190
            |..|:  |||    ||..|.|.::|||||:                   .:|:....::.|::
Frog   466 GEAGV--EGE----VPGSAVLVFDIELLDLIPGLPEGYMFVWNGEVSPNLFEDIDKDQNGEVV-- 522

  Fly   191 YGTRKKERANFFYKRSEFTTAIHLYRRA---------------LDFLDNRDGDPDSEFDKEDLEL 240
                          ..||...||...||               .:...|:|.:.|.:..:|:.:|
Frog   523 --------------LDEFIEYIHAQVRAGKGKLAPGFDPNKIIENMFTNQDRNQDGKITEEEFKL 573

  Fly   241 SNSDTQTLLED 251
            .:.:.:.:.::
Frog   574 KDEEDKEIHDE 584

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zda	NP_001286579.1	FKBP_C	80..172	CDD:278674	25/91 (27%)
		TPR_11	196..284	CDD:290150	11/71 (15%)
		TPR repeat	196..220	CDD:276809	6/38 (16%)
		TPR repeat	252..282	CDD:276809	41/206 (20%)
		TPR_11	255..318	CDD:290150
		TPR repeat	287..313	CDD:276809
		TPR repeat	321..349	CDD:276809
fkbp9	NP_001123385.1	FKBP_C	60..152	CDD:365980
		FKBP_C	172..264	CDD:365980
		FKBP_C	284..375	CDD:365980
		FKBP_C	395..487	CDD:365980	25/91 (27%)
		EFh	510..571	CDD:238008	12/76 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910