Protein Alignment Cth and metB

DIOPT Version :10

• Sequence 1: NP_611352.1
• Gene: Cth / 37143
• FlyBaseID: FBgn0000566
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_418374.1
• Gene: metB / 948434
• ECOCYCID: EG10582
• Length: 386
• Species: Escherichia coli
• Alignment Length: 384
• Identity: 159/384 - (41%)
• Similarity: 228/384 - (59%)
• Gaps: 6/384 - (1%)

  Fly    11 ATKSIHSGQSPDQWKSAAVIPPISLSTTFKQDAPGEHRGYEYSRSGNPTRNVLETCFAALDNAKY 75
            ||.::.||.:.|: :...|:|||.||:|:......|.|.::|||.|||||:|::...|.|:....
E. coli     6 ATIAVRSGLNDDE-QYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAG 69

  Fly    76 GLTFSSGLGATTAVLTM-LSSGDHIIMGDDVYGGTNRLIRQVATRLGISATFVDPTKLDLIKSSI 139
            .:..::|:.|...|.|: |..||.::...|.|||:.||...:|.|......|||......:::::
E. coli    70 AVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAAL 134

  Fly   140 KPETKLVWIESPTNPLVKVADIEAIAQLVHGVRE-DIVLAVDNTFLTSYFQRPLELGADLVCYSL 203
            ..:.|||.:|||:|||::|.|   ||::.|..|| ..|..||||||:...|.||.||||||.:|.
E. coli   135 AEKPKLVLVESPSNPLLRVVD---IAKICHLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSC 196

  Fly   204 TKYMNGHTDVVMGGITMNSEKLYKSLKFLQNAVGIVPSPFDCYQVNRSLKTLSLRMEQHQKNALK 268
            |||:|||:|||.|.:......:...|.:..|.:|:....||.|.:.|.|:||..|||..|:||..
E. coli   197 TKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQA 261

  Fly   269 VAKYLETNPFVEKVLHPSLPSHPQHKIALKQAYGYSGVFSFYIKGELKHSSAFLKALKVFTLAES 333
            :.|||:|.|.|:|:.|||||.:..|:||.:|..|:..:.||.:.|:.:....||..|.:||||||
E. coli   262 IVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAES 326

  Fly   334 LGGYESLAELPSIMTHASVPAEDRKTLGITDGLVRLSVGLEDADDLIKDLEQALEIASK 392
            |||.|||....:.||||.:..|.|...||::.|:|:|.|:||.:|||.|||.....|:|
E. coli   327 LGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cth	NP_611352.1	MetC	9..388	CDD:440391	157/378 (42%)
metB	NP_418374.1	PRK08045	1..386	CDD:169194	159/384 (41%)