Protein Alignment Cth and YHR112C

DIOPT Version :10

• Sequence 1: NP_611352.1
• Gene: Cth / 37143
• FlyBaseID: FBgn0000566
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_011980.1
• Gene: YHR112C / 856512
• SGDID: S000001154
• Length: 378
• Species: Saccharomyces cerevisiae
• Alignment Length: 397
• Identity: 131/397 - (32%)
• Similarity: 194/397 - (48%)
• Gaps: 48/397 - (12%)

  Fly    11 ATKSIHSGQSPDQWKSAAVIPPISLSTTFKQD----APGEHRGY--------EYSRSGNPTRNVL 63
            :|..|| |...|. :...|.|||::||||:.|    .|...|..        .|||..:|....|
Yeast     5 STALIH-GDDKDN-RVTDVAPPINVSTTFRYDDDDLIPWTERENLDFMEKKPVYSRLAHPNSTRL 67

  Fly    64 ETCFA-ALDNAKYGLTFSSGLGATTAVLTMLSSGDHIIMGDDVYGGTNRLIRQVATR-LGISATF 126
            |:.|: .||.  |.:.:||||.|..|.:...:. ..|.:|...:|  .|.|..:.|| .||....
Yeast    68 ESIFSEILDG--YAVIYSSGLAAFYAAMVHYNP-KKIFIGQSYHG--VRAIANILTRNYGIEQHP 127

  Fly   127 VDPTKLDLIKSSIKPETKLVWIESPTNPLVKVADIEAIAQLVHGVREDIVLAVDNTFLTSYFQRP 191
            ::    |:.|.:  .|..:|.:|||.||....:|||::|:..|.  :..:|.||:||.:...|..
Yeast   128 LE----DIEKCA--SEGDIVHLESPVNPYGTSSDIESLARRAHA--KGALLIVDSTFASPPLQYA 184

  Fly   192 LELGADLVCYSLTKYMNGHTDVVMGGITMNSEKLYKSLKFLQNAVGIVPSPFDCYQVNRSLKTLS 256
            ...|||:|.||.|||..||:|::.|.:.:..|...:.||..:..:|...:..:.:.:.|||:|..
Yeast   185 WNFGADIVLYSATKYFGGHSDLLSGVLVVKEEATSRQLKDDRIYLGTNVANLESFMLLRSLRTYE 249

  Fly   257 LRMEQHQKNALKVAKYL-----ETNPFVEKVLHPSLPSHPQHKIALKQAYGYSGVFSFYIKGELK 316
            :|:.:..:||.|:.::|     |.:..::.:.|.||.:....|..|...||.....:.|.|.:.|
Yeast   250 MRITKQSENATKLVRFLSDHQSEFDKVLKTIYHSSLQTEEFVKKQLVGGYGPVFAITLYTKEQCK 314

  Fly   317 HSSAFLKALKVFTLAESLGGYESLAELPSIMTHASVPAEDRKTLGITDGLVRLSVGLEDADDLIK 381
            ...  || ||.|..|.||||.|||.|..: ||.   |..|:.       |:|:|||.|.|:||||
Yeast   315 QLP--LK-LKYFHHATSLGGIESLVEWRA-MTD---PYIDQT-------LIRVSVGCESANDLIK 365

  Fly   382 DLEQALE 388
            ||..||:
Yeast   366 DLASALK 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cth	NP_611352.1	MetC	9..388	CDD:440391	130/395 (33%)
YHR112C	NP_011980.1	CGS_like	20..372	CDD:99738	125/378 (33%)