Protein Alignment Cth and CTH

DIOPT Version :10

• Sequence 1: NP_611352.1
• Gene: Cth / 37143
• FlyBaseID: FBgn0000566
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_001893.2
• Gene: CTH / 1491
• HGNCID: 2501
• Length: 405
• Species: Homo sapiens
• Alignment Length: 381
• Identity: 241/381 - (63%)
• Similarity: 301/381 - (79%)
• Gaps: 1/381 - (0%)

  Fly    10 FATKSIHSGQSPDQWKSAAVIPPISLSTTFKQDAPGEHRGYEYSRSGNPTRNVLETCFAALDNAK 74
            |||::||.||.|:||.|.||:|||||||||||.|||:|.|:|||||||||||.||...||||.||
Human    18 FATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAK 82

  Fly    75 YGLTFSSGLGATTAVLTMLSSGDHIIMGDDVYGGTNRLIRQVATRLGISATFVDPTKLDLIKSSI 139
            |.|.|:|||.||..:..:|.:||.||..|||||||||..||||:..|:..:|||.:|:.|::::|
Human    83 YCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI 147

  Fly   140 KPETKLVWIESPTNPLVKVADIEAIAQLVHGVREDIVLAVDNTFLTSYFQRPLELGADLVCYSLT 204
            .|||||||||:||||..||.|||..|.:|| ...||:|.|||||::.||||||.||||:..||.|
Human   148 TPETKLVWIETPTNPTQKVIDIEGCAHIVH-KHGDIILVVDNTFMSPYFQRPLALGADISMYSAT 211

  Fly   205 KYMNGHTDVVMGGITMNSEKLYKSLKFLQNAVGIVPSPFDCYQVNRSLKTLSLRMEQHQKNALKV 269
            ||||||:|||||.:::|.|.|:..|:||||::|.||||.|||..||.||||.:|||:|.||.:.|
Human   212 KYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAV 276

  Fly   270 AKYLETNPFVEKVLHPSLPSHPQHKIALKQAYGYSGVFSFYIKGELKHSSAFLKALKVFTLAESL 334
            |::||:||:||||::|.|||||||::..:|..|.:|:.:|||||.|:|:..|||.||:|||||||
Human   277 AQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESL 341

  Fly   335 GGYESLAELPSIMTHASVPAEDRKTLGITDGLVRLSVGLEDADDLIKDLEQALEIA 390
            ||:|||||||:|||||||...||..|||:|.|:||||||||.:||::||:|||:.|
Human   342 GGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cth	NP_611352.1	MetC	9..388	CDD:440391	239/377 (63%)
CTH	NP_001893.2	Cys_Met_Meta_PP	19..379	CDD:395837	227/360 (63%)