Protein Alignment Sec6 and tnfaip2b

DIOPT Version :9

• Sequence 1: NP_611351.1
• Gene: Sec6 / 37142
• FlyBaseID: FBgn0266671
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_697839.5
• Gene: tnfaip2b / 569366
• ZFINID: ZDB-GENE-081107-56
• Length: 613
• Species: Danio rerio
• Alignment Length: 690
• Identity: 131/690 - (18%)
• Similarity: 276/690 - (40%)
• Gaps: 136/690 - (19%)

  Fly    95 YDALEVVREENTK-HS-QYATAMENLK-HIFNVDASVQKTMALIEDDKLLNAHQCLADLENSRDD 156
            :..|.:.::...| || :..|..:||| |.| |||..|   .::.:|:|....|         |.
Zfish     5 HGVLNLFKKNGKKSHSPEIPTFKQNLKAHRF-VDACKQ---LILREDRLFVLKQ---------DG 56

  Fly   157 LLYELHKQPKQHASDKITLKRHFEKVDTVSQELEKKLRLILSRTLNTLRKKPTIIVTALRIIERE 221
            :..::....::..|:....|.:.:.::.|.|.||..|.|       ..:::..::..|:..:..|
Zfish    57 IGSKMRLVEEEEDSEARLAKDYEDLLECVRQTLENSLEL-------QSKEEQEMLKEAVHAVLEE 114

  Fly   222 EKND----QFALQQQKVTGFLPPGRPKAWRRMIMDVLQQSVITRIEGSKLEERADNKMWLVRDLE 282
            ||.|    .|..:|:      |..||:..:::...:|:..|..|:|.:.::...|.:..:.:.:.
Zfish   115 EKQDIRWEGFQEKQR------PSWRPRRCKQIHEALLEMLVQRRMEEAPIDLSIDVRSSMQQSII 173

  Fly   283 ILRQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDNIVRSGLEGNEYVSMMAWVTH 347
            ...:.:.|||..|.:....|:|...::...|...||:..::.|..:....|...:.|.::.||..
Zfish   174 CKAKRLKEDLLKVVTWVSCCYPEELNVCQFYATLYHKAFAARLREVAEFTLCDEDCVLILQWVNQ 238

  Fly   348 TYPGV----ELMSHPDLNVDVHRQIGTLLRPEHLKALEDEYLQNMQRNFQEWMTKAAETEKQEWF 408
            .||.:    |:....|     ..::..||..:.|..||.::|.|.:|...:.:....:.|:..|.
Zfish   239 DYPSILNCREIKERID-----QAKLDPLLPEDLLAPLEQQFLSNEKREVSKCLHNILDREETAWR 298

  Fly   409 TETVPDQDEEYYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMSIQQVEIFGQTYLKNVIELK 473
            ...:|...::.|.....:.:.|...:|::.|..:..:.| ||..::.|.     ..:||   :.:
Zfish   299 DGKLPQLMDQVYCCPQAIDVIQFFHRHVEFTEQVLGDKT-KARRITCQM-----SNFLK---DYR 354

  Fly   474 EHHFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHYEDFERLLATFQRIRAHAA 538
            ..|.:              ::.:.|...|:...:...|..:.|
Zfish   355 AFHAK--------------VIKSKQPNTEVVLMVNLSYLIQCR---------------------- 383

  Fly   539 SYLLEEAFLDME------------------CHF--------NDLF----TAKWLASNIAV-DTIC 572
            .|:::.|.|..|                  |:|        .||:    :.:||.::..| :.:.
Zfish   384 DYIIKNAHLFPEDVKTDCLSLLTGMTESSHCYFTSNMHREMKDLYRKVGSNEWLKNSKGVCEKLL 448

  Fly   573 VTLDDYFQDYNHLRPNNFEMVINEAQKLLAKRYIRALLSKRLSKPRAECDAITRKIKTEAKRFKL 637
            ..||.:.|.:|:|.....:.::....|.....|||.::.:::.        ::.|.:.:.....|
Zfish   449 AKLDRHIQKFNNLDKTCCQELLGRIHKEFLAEYIRKMMKQKIK--------LSNKEQQQLAASAL 505

  Fly   638 FF--EKIAPKISLSDSPL----DLISTLSALLS-SDIELLVLDLHTLLGSYPSLNEDHLVRLFYI 695
            .|  |:|...::.:.|.:    |::..|:.||. .|.:.:.|:|..|:.:||.|:|.|:.....:
Zfish   506 CFNSERIHTFLTSAGSNMDWLKDILPKLAGLLKLQDPDSVKLELVNLMRAYPDLSERHISAWLKL 570

  Fly   696 RNDVKAAEVREKVQDAMKSKKAMVSIAKQDCI-FKEIVFS 734
            :.::..::::..::....|::.|  ...||.: |.:..||
Zfish   571 KGNLSPSDLKMILKSVACSQEEM--SGNQDLLDFSKSFFS 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec6	NP_611351.1	Sec6	179..731	CDD:283659	109/598 (18%)
tnfaip2b	XP_697839.5	Sec6	72..596	CDD:303062	107/596 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594427
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5173
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850