Protein Alignment Sec6 and exoc3

DIOPT Version :9

• Sequence 1: NP_611351.1
• Gene: Sec6 / 37142
• FlyBaseID: FBgn0266671
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001005685.1
• Gene: exoc3 / 448187
• XenbaseID: XB-GENE-972389
• Length: 747
• Species: Xenopus tropicalis
• Alignment Length: 745
• Identity: 292/745 - (39%)
• Similarity: 458/745 - (61%)
• Gaps: 30/745 - (4%)

  Fly     6 LEEQARQA---ALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTGMQGQLDGVRVGLKQL 67
            :||..|:|   |::.:..|||||.||:||||||.|.|||||||||.||..:|.||||||.||.||
 Frog     1 MEEPDREAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLNQL 65

  Fly    68 ETCMQDVREVRRRMDEVERLLRGVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDASVQKTM 132
            ...:.||:::::.:.:|.:..|......::|:.|::...:|||.|.|:||||:||:|...|::|.
 Frog    66 HNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQ 130

  Fly   133 ALIEDDKLLNAHQCLADLENSRDDLLYELHKQPKQHASDKITLKRHFEKVDTVSQELEKKLRLIL 197
            .|||..:||.||:.|.|||.|||||:||.::...::..|...::.:|.||..:|:||.|:|.:::
 Frog   131 DLIEQGELLQAHRKLMDLECSRDDLMYEQYRMDSKNTHDMNLIQNYFGKVHPLSEELAKQLWMVI 195

  Fly   198 SRTLNTLRKKPTIIVTALRIIEREEKNDQFALQQQKVTGFLPPGRPKAWRRMIMDVLQQSVITRI 262
            .|::.|:|:.||::|:.:||||||||.|:..:.::|.|||:||||||.|:..:.|||.:::||||
 Frog   196 QRSIVTVRRDPTLLVSVVRIIEREEKVDRRMMDRKKQTGFIPPGRPKKWKDKMFDVLDKTIITRI 260

  Fly   263 EGSKLEERADNKMWLVRDLEILRQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDN 327
            |||:.:.|..:||||||.|||:|:.:||||.::|:|.|.||||.|:||...:..||:.|||.:..
 Frog   261 EGSQADTRESDKMWLVRHLEIIRRYMLEDLIIIKNLMVQCFPPSYNIFNRVLDLYHQALSSRIQE 325

  Fly   328 IVRSGLEGNEYVSMMAWVTHTYPGVELMSHPDLNVDVH-RQIGTLLRPEHLKALEDEYLQNMQRN 391
            :....||.||.||::.||.:||..||:|.:|:|..::: :.:..||..:.:..|..:|:..::.|
 Frog   326 LASEELEANEIVSLLTWVLNTYQSVEMMGNPELIPEINVKSLKPLLSQDIVDQLLHKYMATLRSN 390

  Fly   392 FQEWMTKAAETEKQEWFTETVPDQDEE-YYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMSI 455
            ...|:.||.||:|::|...|.|:.|:: |:.|:.|.|:|||.:|:|||...|..:|..|.|.:.:
 Frog   391 IIAWLRKALETDKKDWDKNTEPEADQDGYFQTTLPAIVFQMFEQNLQVAAQISDDLKKKVLHLCL 455

  Fly   456 QQVEIFGQTYLKNVIELKEHHFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHY 520
            ||:..|...|.:.....||.|.|:|.....:..|:|.|:||.|...|....:|:.|        .
 Frog   456 QQMNTFLNRYAEEAQLYKEDHLRSRQHPACYVQYMIAIINNCQTFKESIVSLKRKY--------L 512

  Fly   521 EDFERLL--------ATFQRIRAHAASYLLEEAFLDMECHFNDLFTAKWLASNIAVDTICVTLDD 577
            .|.:.::        .|...|.......||:|.|:|:|.|.|||.|.|||..:..|||||||::|
 Frog   513 RDEDDIIGFGSSAMDTTLDSIANDGCCSLLDEVFMDLEQHLNDLMTRKWLGGSNTVDTICVTIED 577

  Fly   578 YFQDYNHLRPN-NFEMVINEAQKLLAKRYIRALLSKRLSKPRAE--CDAITRKIKTEAKRFKLFF 639
            ||.|:..::.: |.||.|...:|::.: ||:|::.||:|...||  .:...:.|| ||::||..|
 Frog   578 YFNDFAKIKTHYNQEMTIKAHRKVVTE-YIKAIMQKRISFRNAEERKEGAEKMIK-EAEQFKFLF 640

  Fly   640 EKI-APKISLSDSPLDLISTLSALLS-SDIELLVLDLHTLLGSYPSLNEDHLVRLFYIRNDVKAA 702
            ::: |..|..:|...:.|..::.:|. :|..||.|::.||:|.||.|.:||:..|..:|.|. :.
 Frog   641 KRLTAGFIEDTDGLCNTIIDIAEVLKLTDPSLLYLEVSTLVGRYPDLRDDHIAALLAVRGDA-SR 704

  Fly   703 EVREKVQDAMKSKKAMVSIAKQDCIFKEIV 732
            |:::.:.:.::..:...| |....|||:|:
 Frog   705 EMKQTIIETVEQSQRQQS-ANYTPIFKDII 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec6	NP_611351.1	Sec6	179..731	CDD:283659	211/566 (37%)
exoc3	NP_001005685.1	Sec6	177..732	CDD:283659	211/566 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	378	1.000	Domainoid score	I842
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H38296
Inparanoid	1	1.050	525	1.000	Inparanoid score	I1220
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D335038at33208
OrthoFinder	1	1.000	-	-		FOG0002440
OrthoInspector	1	1.000	-	-		oto104619
Panther	1	1.100	-	-	LDO	PTHR21292
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1313
SonicParanoid	1	1.000	-	-		X4764
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190