Protein Alignment Sec6 and Exoc3

DIOPT Version :9

• Sequence 1: NP_611351.1
• Gene: Sec6 / 37142
• FlyBaseID: FBgn0266671
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: NP_001020135.1
• Gene: Exoc3 / 252881
• RGDID: 621790
• Length: 755
• Species: Rattus norvegicus
• Alignment Length: 743
• Identity: 284/743 - (38%)
• Similarity: 440/743 - (59%)
• Gaps: 22/743 - (2%)

  Fly     3 LQQLEEQARQAALKDIQNMLQRPGQLEKVEQYRHRIARKKASVEALLKTGMQGQLDGVRVGLKQL 67
            :::.:.:|...|::.:..|||||.||:||||||.|.|||||||||.||..:|.||||||.||.||
  Rat    11 MKETDLEAVATAVQRVAGMLQRPDQLDKVEQYRRREARKKASVEARLKAAIQSQLDGVRTGLSQL 75

  Fly    68 ETCMQDVREVRRRMDEVERLLRGVPEVYDALEVVREENTKHSQYATAMENLKHIFNVDASVQKTM 132
            ...:.||:::::.:.:|.:..|......::|:.|::...:|||.|.|:||||:||:|...|::|.
  Rat    76 HNALNDVKDIQQSLADVSKDWRQSINTIESLKDVKDAVVQHSQLAAAVENLKNIFSVPEIVRETQ 140

  Fly   133 ALIEDDKLLNAHQCLADLENSRDDLLYELHKQPKQHASDKITLKRHFEKVDTVSQELEKKLRLIL 197
            .|||...||.||:.|.|||.|||.|:.|.::....:..|...:..:|.....:|.||.|:|.::|
  Rat   141 DLIEQGALLQAHRKLMDLECSRDGLMCEQYRMDSGNKRDMTLIHGYFGSTQGLSDELAKQLWMVL 205

  Fly   198 SRTLNTLRKKPTIIVTALRIIEREEKNDQFALQQQKVTGFLPPGRPKAWRRMIMDVLQQSVITRI 262
            .|:|.|:|:.||::|:.:||||||||.|:..|.::|.|||:||||||.|:..:..||.::|.|||
  Rat   206 QRSLVTVRRDPTLLVSVVRIIEREEKIDRRILDRKKQTGFVPPGRPKNWKEKMFAVLDRTVTTRI 270

  Fly   263 EGSKLEERADNKMWLVRDLEILRQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDN 327
            ||::.:.|..:||||||.|||:|:.:|:||.:.|:|.|.|||||||||...:..||:.||..:.:
  Rat   271 EGTQADTRESDKMWLVRHLEIIRKYVLDDLVIAKNLLVQCFPPHYDIFKNLLSMYHQALSIRMQD 335

  Fly   328 IVRSGLEGNEYVSMMAWVTHTYPGVELMSHPDL--NVDVHRQIGTLLRPEHLKALEDEYLQNMQR 390
            :....||.||.||::.||.:||...|:|.:.:|  .|||: .:..||.|..:..|.|.|:..:..
  Rat   336 LASEDLEANEIVSLLTWVLNTYTSAEMMGNVELAPEVDVN-ALEPLLSPNVVSELLDTYMSTLTS 399

  Fly   391 NFQEWMTKAAETEKQEWFTETVPDQDEE-YYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMS 454
            |...|:.||.||:|::|..||.|:.|:: ||.|:.|.|:|||.:|:|||...|.::|..|.||:.
  Rat   400 NIIAWLRKALETDKKDWSKETEPEADQDGYYQTTLPAIVFQMFEQNLQVAAQISEDLKTKVLVLC 464

  Fly   455 IQQVEIFGQTYLKNVIELKEHHFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYW-PKSRTE 518
            :||:..|...|.:.....||.|.|||.....:..|::.|:||.|...|....:|:.|. |::...
  Rat   465 LQQMNSFLSRYKEEAQLYKEEHLRNRQHPHCYVQYMVAIINNCQTFKESIISLKRKYLKPETEES 529

  Fly   519 HYEDFERLLATFQRIRAHAASYLLEEAFLDMECHFNDLFTAKWLASNIAVDTICVTLDDYFQDYN 583
            ..:....:......|.....|.||||.|||:|.|.|:|.|.||:..:.|||.||||::|||.|:.
  Rat   530 LCQSQPSMDGILDAIAKEGCSSLLEEVFLDLEQHLNELMTKKWMLGSNAVDIICVTVEDYFNDFA 594

  Fly   584 HLRPNNFEMVINEAQKLLAKRYIRALLSKRLS-------KPRAECDAITRKIKTEAKRFKLFFEK 641
            .::....:.:..||.:.:...|:||::.||:|       |..||      |:..||::.:..|.|
  Rat   595 KIKKPYKKRMTAEAHRRVVVEYLRAVMQKRISFRSAEERKEGAE------KMVREAEQLRFLFRK 653

  Fly   642 IAPKISL-SDSPLDLISTLSALLS-SDIELLVLDLHTLLGSYPSLNEDHLVRLFYIRNDVKAAEV 704
            :|..... :|...|.|..::.::. :|..||.|::.||:..||.:.:||:..|..:|.|. :.::
  Rat   654 LASGFGEDADGHCDTIVAVAEVIKLTDPSLLYLEVSTLVSKYPDIRDDHIGALLALRGDA-SRDM 717

  Fly   705 REKVQDAMKSKKAMVSIAKQDCIFKEIV 732
            ::.:.:.:: :..|.:......||:|||
  Rat   718 KQTIMETLE-QGPMQASPNYVPIFQEIV 744

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec6	NP_611351.1	Sec6	179..731	CDD:283659	206/564 (37%)
Exoc3	NP_001020135.1	Sec6	187..743	CDD:399204	206/564 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352495
Domainoid	1	1.000	374	1.000	Domainoid score	I850
eggNOG	1	0.900	-	-		E1_COG5173
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38296
Inparanoid	1	1.050	509	1.000	Inparanoid score	I1274
OMA	1	1.010	-	-		QHG55512
OrthoDB	1	1.010	-	-		D335038at33208
OrthoFinder	1	1.000	-	-		FOG0002440
OrthoInspector	1	1.000	-	-		oto97927
orthoMCL	1	0.900	-	-		OOG6_103744
Panther	1	1.100	-	-	LDO	PTHR21292
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4764
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770