Protein Alignment Sec6 and exoc3l2

DIOPT Version :9

• Sequence 1: NP_611351.1
• Gene: Sec6 / 37142
• FlyBaseID: FBgn0266671
• Length: 738
• Species: Drosophila melanogaster
• Sequence 2: XP_012824751.2
• Gene: exoc3l2 / 100486119
• XenbaseID: XB-GENE-982090
• Length: 780
• Species: Xenopus tropicalis
• Alignment Length: 747
• Identity: 163/747 - (21%)
• Similarity: 306/747 - (40%)
• Gaps: 144/747 - (19%)

  Fly     8 EQARQAALKDIQNMLQRPGQLEKVEQY-----------------RHRIARKKASVEALLKTGMQG 55
            |:.|:...:.:.:.::|.|.|||:...                 ..|..|:|:...:||..|.:.
 Frog    32 EEEREVKRESLGSDVKRRGTLEKIAGLSPFFKGGKGLLGGWGTPEKRRGRRKSEDVSLLSLGRKK 96

  Fly    56 QLD-------GVRVGLKQLETCM----------QDVREVRRRMDEVERLLRGVPEVYDALEVVRE 103
            .::       |...|:|:|....          |..|         |.::..|||..:|    .:
 Frog    97 DINVGDEGGGGPGGGVKRLSFLWLGGSSGSGGNQSQR---------ESMVEAVPERSEA----EQ 148

  Fly   104 ENTKHSQYATAMENLKHIFNVDASVQKTMALIEDDKLLNAHQCLADLE------NSRDDLLYELH 162
            ||.|..:..:.:|.|:              ||:...|.:|.|.:.:||      .|.:..|
 Frog   149 ENEKTREPLSVLEILQ--------------LIQCRDLRSADQHIIELEAECDGGTSPEGGL---- 195

  Fly   163 KQPKQHASDKITLKRHFEKVDTVSQELEKKLRLILSRTLN---TLRKKPTIIVTALRIIEREEKN 224
            |.|.:.|.| :||         :.:.|.|::..::..:||   |..|...:|    .:|.:||..
 Frog   196 KSPGRQAKD-VTL---------LYEALMKEMWAVVEESLNNKGTHHKLDEVI----GVILQEEGR 246

  Fly   225 DQFALQQQKVTGFLPPGRP---KAWRRMIMDVLQQSVITRIEG--SKLEERADNKMWLVRDLEIL 284
            :.            |||..   :.|.:.|...::|.:...:||  ..|..:||.          :
 Frog   247 EG------------PPGTKDMRRQWMKAIGRSVEQRLKNNLEGKMGSLSSQADR----------V 289

  Fly   285 RQIILEDLRVVKSLCVPCFPPHYDIFGEYVKFYHEGLSSYLDNIVRSGLEGNEYVSMMAWVTHTY 349
            ::|.:|||..||:..|..:|..:::|..|:..||.|:|.:|....:..||.||...::.|.::.|
 Frog   290 KRIAVEDLTTVKNHLVCSYPKDFEVFRVYLSAYHSGISDWLSTTAQRNLETNEIYFILDWNSNVY 354

  Fly   350 PGVELMSHPDLNVDVH-RQIGTLLRPEHLKALEDEYLQNMQRNFQEWMTKAAETEKQEWFTETVP 413
            .. :::|..:::..:: .::||||.||....||.:.:..:|....:.:.:...||::.|..|...
 Frog   355 YR-DVLSRSEISPLINPLELGTLLSPETRSMLEQQCVNAVQLRISQRLEEELRTEQEHWKEEHKI 418

  Fly   414 DQDEEYYHTSAPVIIFQMIDQHLQVTNTIHQELTFKALVMSIQQVEIFG---QTYLKNVIELKEH 475
            |..:..:...:    .|::..|::....|.:..   .:|||...:..|.   .::.|.|......
 Frog   419 DDIQSTFSMRS----IQIMKPHVERAPVISKGF---GIVMSQSCLRCFSDFLHSFQKAVDRFHAE 476

  Fly   476 HFRNRDQIKYFTHYIITIVNNSQQMVELAQQMKQLYWPKSRTEHYEDFERLLATFQRIRAHAASY 540
            .....:..:.:.:.||.|||......|.|.:|.|  :..|:.|  |...:...:..||.......
 Frog   477 QNGLNESSEAYIYRIIGIVNCCPPFREFANRMAQ--FESSQGE--EPLRQTEKSLDRIINLGTKT 537

  Fly   541 LLEEAFLDMECHFNDLFTAKWLASNIAVDTICVTLDDYFQDYNHLRPNNFEMVINEAQKLLAKRY 605
            :.:....|::.....|...:||:|:.|.:.:...|.|:......:....:::|::|..:.:....
 Frog   538 ICDLVLQDLKPFSRKLLGRRWLSSSDACEGMVAALTDHVPALRKINQGPYQVVVSELHRRVFLEL 602

  Fly   606 IRALLSKRL----SKPRAECDAITRKIKTEAKRFKLFFEKI-APKISLSDSPLDLISTLSALL-S 664
            :|.||..::    ||.|.:   ::.|:|.||::....|.|: :|:.||.    .||..|:.:| .
 Frog   603 VRPLLQGKMNCNTSKTRKK---VSNKLKDEARQLGQIFNKLESPQTSLD----HLIPRLAEILVL 660

  Fly   665 SDIELLVLDLHTLLGSYPSLNEDHLVRLFYIR 696
            .|...|.:::..|:..:|...:.|||.|..||
 Frog   661 EDTVSLQMEVGMLVSDFPDFRKHHLVALMDIR 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sec6	NP_611351.1	Sec6	179..731	CDD:283659	119/536 (22%)
exoc3l2	XP_012824751.2	Sec6	204..729	CDD:418703	122/544 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D391172at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020