| Sequence 1: | NP_611350.1 | Gene: | Atg7 / 37141 | FlyBaseID: | FBgn0034366 | Length: | 684 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_003959.3 | Gene: | UBA3 / 9039 | HGNCID: | 12470 | Length: | 463 | Species: | Homo sapiens |
| Alignment Length: | 351 | Identity: | 79/351 - (22%) |
|---|---|---|---|
| Similarity: | 124/351 - (35%) | Gaps: | 108/351 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 330 PDL-----NLEIISQT-KCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHA 388
Fly 389 DAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKL-----VQ 448
Fly 449 DHDVIFLLTDSRESRWLPTLLGAAKEKIVIN---AALGFDSYLVMRHGTTRKEAGDDGQEIEGLK 510
Fly 511 CINGDQLGCYFCN------DVTAPGNSLKDRTLDQQCTV-TRPGVSNIAASYAVELLVALLQHPR 568
Fly 569 KELAPAYYAQSGRGRSEETEEKVPEGLLGIL--------PHSIRGMLCN-----YENILPATQK- 619
Fly 620 ----FAQC------IACSAAV-LNEY 634 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Atg7 | NP_611350.1 | E1_like_apg7 | 11..682 | CDD:273590 | 79/351 (23%) |
| UBA3 | NP_003959.3 | Interaction with UBE2M N-terminus | 53..70 | 3/15 (20%) | |
| Uba3_RUB | 71..368 | CDD:238765 | 75/334 (22%) | ||
| Interaction with UBE2M N-terminus | 157..161 | 1/3 (33%) | |||
| Interaction with UBE2M N-terminus | 192..217 | 4/24 (17%) | |||
| Interaction with NEDD8 | 227..229 | 0/1 (0%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 242..248 | 1/5 (20%) | |||
| Interaction with NAE1. /evidence=ECO:0000269|PubMed:12740388 | 292..295 | 0/2 (0%) | |||
| Interaction with UBE2M N-terminus | 331..338 | 4/6 (67%) | |||
| Interaction with NEDD8 | 352..357 | ||||
| Interaction with UBE2M core domain | 368..463 | ||||
| E2_bind | 376..461 | CDD:462611 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||