Protein Alignment Atg7 and ATG7

DIOPT Version :9

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_012041.1
• Gene: ATG7 / 856576
• SGDID: S000001214
• Length: 630
• Species: Saccharomyces cerevisiae
• Alignment Length: 701
• Identity: 261/701 - (37%)
• Similarity: 379/701 - (54%)
• Gaps: 98/701 - (13%)

  Fly     1 MSTEKEIILQFAP-WESFVSPTFWHKLAELKLDHDRLSDSKRSITGHYTNRNASGCLLEVDYTAY 64
            ||:|:  :|.:|| ::||:..:|:.:|:.||||..:|..:.:.:|.:....|......:|.....
Yeast     1 MSSER--VLSYAPAFKSFLDTSFFQELSRLKLDVLKLDSTCQPLTVNLDLHNIPKSADQVPLFLT 63

  Fly    65 NRMAKPPKFSHSAI------GTIYNKNTIEEFKALDKLQLLADEGKELLADMCSGGALRDPSLLT 123
            ||..:  |.::...      |:|:|.|.::|||.|||...|.....|     |....::|.:...
Yeast    64 NRSFE--KHNNKRTNEVPLQGSIFNFNVLDEFKNLDKQLFLHQRALE-----CWEDGIKDINKCV 121

  Fly   124 RFFVLSFADLKCHSYYYWFAFPCPLTPTLKLQGAVQKLRDLPNSSSYIMALKALPTESQNFFILY 188
            .|.::||||||.:.:|||...||...|:    ..|..:|..|       :||.|.::.|.:|
Yeast   122 SFVIISFADLKKYRFYYWLGVPCFQRPS----STVLHVRPEP-------SLKGLFSKCQKWF--- 172

  Fly   189 ANVEKNIFEARSLSSLDDK--NVEFC------YFGFADPSEYEH-PAWIMRNYAAFLLQQCPSFV 244
               :.|..:...:...||:  |.:.|      .....|.|..|: |:.:.:|:.:.|....|..:
Yeast   173 ---DVNYSKWVCILDADDEIVNYDKCIIRKTKVLAIRDTSTMENVPSALTKNFLSVLQYDVPDLI 234

  Fly   245 GKPLKFLGLRHNQ---QMNIDDSLVWKVIQTEACDLSQSENIKFVGWELNKNGKMGPRMVCMRDS 306
              ..|.|.:|.|:   .:|...:.:      :....|.:.::|..|||.|..||:.||:|.:...
Yeast   235 --DFKLLIIRQNEGSFALNATFASI------DPQSSSSNPDMKVSGWERNVQGKLAPRVVDLSSL 291

  Fly   307 MDPAKLAENSVNLNLKLMKWRLVPDLNLEIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDS 371
            :||.|:|:.||:|||||||||::|||||:||..||.||.|||||||.|:|.|::||.:.||.:|:
Yeast   292 LDPLKIADQSVDLNLKLMKWRILPDLNLDIIKNTKVLLLGAGTLGCYVSRALIAWGVRKITFVDN 356

  Fly   372 GKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGH-TIGESLLAQ 435
            |.|.:||||||.||...|.   .:.||..||..||.|.|..:..|..|.|||.|| .:.|.  ||
Yeast   357 GTVSYSNPVRQALYNFEDC---GKPKAELAAASLKRIFPLMDATGVKLSIPMIGHKLVNEE--AQ 416

  Fly   436 TKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTLLGAAKEKIVINAALGFDSYLVMRHGTTRKEAG 500
            .|:..: :..|:::||:||||.|||||||||:||...:.|.|||||||||||||||||...::
Yeast   417 HKDFDR-LRALIKEHDIIFLLVDSRESRWLPSLLSNIENKTVINAALGFDSYLVMRHGNRDEQ-- 478

  Fly   501 DDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLKDRTLDQQCTVTRPGVSNIAASYAVELLVALLQ 565
                        :..|||||||:||.||.:||.||||||.||||||||:.:|:|.||||:.:|||
Yeast   479 ------------SSKQLGCYFCHDVVAPTDSLTDRTLDQMCTVTRPGVAMMASSLAVELMTSLLQ 531

  Fly   566 HPRKELAPAYYAQSGRGRSEETEEKVPEGLLGILPHSIRGMLCNYENILPATQKFAQCIACSAAV 630
                      ...||   ||.|       :||.:||.|||.|.|:..:...|..:..|.|||..|
Yeast   532 ----------TKYSG---SETT-------VLGDIPHQIRGFLHNFSILKLETPAYEHCPACSPKV 576

  Fly   631 LNEYKKEGHAFLFKTFETAKFLEDLTGIS----EFKRLNSEIIDFDDEEFD 677
            :..:...|..|:.|..|...:||:::|:|    |.:||.:::.:::|:|.|
Yeast   577 IEAFTDLGWEFVKKALEHPLYLEEISGLSVIKQEVERLGNDVFEWEDDESD 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	ATG7_N	9..303	CDD:293029	81/312 (26%)
		E1_like_apg7	11..682	CDD:273590	257/691 (37%)
		Apg7	341..658	CDD:238763	146/317 (46%)
ATG7	NP_012041.1	E1_like_apg7	9..628	CDD:273590	257/691 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346638
Domainoid	1	1.000	225	1.000	Domainoid score	I434
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4662
Inparanoid	1	1.050	383	1.000	Inparanoid score	I340
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55251
OrthoFinder	1	1.000	-	-		FOG0005140
OrthoInspector	1	1.000	-	-		oto99974
orthoMCL	1	0.900	-	-		OOG6_102679
Panther	1	1.100	-	-	LDO	PTHR10953
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R111
SonicParanoid	1	1.000	-	-		X3660
TreeFam	1	0.960	-	-
	15	14.790