DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atg7 and UBA3

DIOPT Version :9

Sequence 1:	NP_611350.1	Gene:	Atg7 / 37141	FlyBaseID:	FBgn0034366	Length:	684	Species:	Drosophila melanogaster
Sequence 2:	NP_015391.1	Gene:	UBA3 / 856179	SGDID:	S000006270	Length:	299	Species:	Saccharomyces cerevisiae

Alignment Length:	349	Identity:	72/349 - (20%)
Similarity:	120/349 - (34%)	Gaps:	90/349 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   341 KCLLFGAGTLGCAVARNLLSWGF-KHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQR 404
            |.|:.|||.|||.:.:||....| |.:.::|...:..:|..||.|:...|.   .:.||..|||.
Yeast     4 KILVLGAGGLGCEILKNLTMLSFVKQVHIVDIDTIELTNLNRQFLFCDKDI---GKPKAQVAAQY 65

  Fly   405 LKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTLL 469
            :....|..|...:|.::.    |:..|..                .|..|:::.          |
Yeast    66 VNTRFPQLEVVAHVQDLT----TLPPSFY----------------KDFQFIISG----------L 100

  Fly   470 GAAKEKIVINAAL-------GFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYFCNDVTA 527
            .|.:.:..||..|       .::..:....|.|....|.....|.|:       ..|:.|:..|.
Yeast   101 DAIEPRRFINETLVKLTLESNYEICIPFIDGGTEGLKGHVKTIIPGI-------TACWECSIDTL 158

  Fly   528 PGNSLKDRTLDQQCTVTRPGVSN--IAASYAVELLVALLQHP--------RKELAPAYYAQSGRG 582
            |         .||.||....::|  ....:.|| .|:.:|:|        ..|.......:....
Yeast   159 P---------SQQDTVPMCTIANNPRCIEHVVE-YVSTIQYPDLNIESTADMEFLLEKCCERAAQ 213

  Fly   583 RSEETEEKVPEGLLGILPHSIRGMLCNYENILPATQKFAQCIA--CSAAVLNEYK-----KEGHA 640
            .|..||:.....:|||:           ::|:|:.......:|  |...::..|.     :.|:.
Yeast   214 FSISTEKLSTSFILGII-----------KSIIPSVSTTNAMVAATCCTQMVKIYNDLIDLENGNN 267

  Fly   641 FLFKTFETAKFLEDLTGISEFKRL 664
            |.........|:...    :|:||
Yeast   268 FTLINCSEGCFMYSF----KFERL 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	ATG7_N	9..303	CDD:293029
		E1_like_apg7	11..682	CDD:273590	72/349 (21%)
		Apg7	341..658	CDD:238763	69/341 (20%)
UBA3	NP_015391.1	Uba3_RUB	4..294	CDD:238765	72/349 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900