Protein Alignment Atg7 and Atg7

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001240646.1
• Gene: Atg7 / 74244
• MGIID: 1921494
• Length: 741
• Species: Mus musculus
• Alignment Length: 717
• Identity: 291/717 - (40%)
• Similarity: 414/717 - (57%)
• Gaps: 79/717 - (11%)

  Fly     9 LQFAPWESFVSPTFWHKLAELKLDHDRLSDSKRSITGHYTNRNASG--CLLEVDYTAYNRMAKPP 71
            |||||:.|.:...|||:|.:.||:..||.::.:.|.|:|.|.:::|  ..|.::::|::..|..|
Mouse    52 LQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSASTP 116

  Fly    72 KFSHSAIGTIYNKNTIEEFKALDKLQLLADEGKELLADMCSGGALRDPSLLTRFFVLSFADLKCH 136
            .....|:||::|.||:|.||..||..||.....|:...:.||.||.:|.||.:|.:|:|||||.:
Mouse   117 AHCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKY 181

  Fly   137 SYYYWFAFPCPLTPTLKLQGAVQKLR-----DLPNSSSYIMALK-------------ALPTESQN 183
            .:||||.  |   |.|.|..::..:|     |...|...|.||:             |||
Mouse   182 HFYYWFC--C---PALCLPESIPLIRGPVSLDQRLSPKQIQALEHAYDDLCRAEGVTALP----- 236

  Fly   184 FFILYANVEKNIFEARSLSSLDDKNVEF-------CYFGFADPSEY-EHPAWIMRNYAAFLLQQC 240
             :.|:...:..:     |.||.....:|       ...|..||... ::|.|.:||   ||:...
Mouse   237 -YFLFKYDDDTV-----LVSLLKHYSDFFQGQRTKITVGVYDPCNLAQYPGWPLRN---FLVLAA 292

  Fly   241 PSFVG--KPLKFLGLRHNQQMNIDDSLVWKVIQTEACDLSQSENI-KFVGWELNKNGKMGPRMVC 302
            ..:.|  :.::.|..|........|.....:.:.:..:::.|.:. |.||||.|:.|.||||||.
Mouse   293 HRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVN 357

  Fly   303 MRDSMDPAKLAENSVNLNLKLMKWRLVPDLNLEIISQTKCLLFGAGTLGCAVARNLLSWGFKHIT 367
            :...|||.:|||:||:||||||.|||||.|:|:.:...||||.|||||||.|||.|:.||.:|:|
Mouse   358 LSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVT 422

  Fly   368 LLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPGHTIGES- 431
            .:|:.|:.:||||||.||...|.:.|.:.||..||:||::|.|.....|:.:.||||||.:..|
Mouse   423 FVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSD 487

  Fly   432 -LLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTLLGAAKEKIVINAALGFDSYLVMRHGTT 495
             .:.|.:..::.:|:|:.:|||||||.|:||||||||::.|:|.|:|||||||||:::|||||..
Mouse   488 VTMEQARRDVEQLEQLIDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLK 552

  Fly   496 R-KEAG-------------DDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLKDRTLDQQCTVTRP 546
            : |:.|             |.|..:  ...|.|.:|||||||||.|||:|.:||||||||||:||
Mouse   553 KPKQQGAGDLCPSHLVAPADLGSSL--FANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQCTVSRP 615

  Fly   547 GVSNIAASYAVELLVALLQHPRKELAPAYYAQSGRGRSEETEEKVPEGLLGILPHSIRGMLCNYE 611
            |::.||.:.||||:|::||||....|   .|.|...|..|     |...||::||.|||.|..::
Mouse   616 GLAVIAGALAVELMVSVLQHPEGGYA---IASSSDDRMNE-----PPTSLGLVPHQIRGFLSRFD 672

  Fly   612 NILPATQKFAQCIACSAAVLNEYKKEGHAFLFKTFETA-KFLEDLTGISEFKRLN--SEIIDFDD 673
            |:||.:..|.:|.|||..||::|::||..||.|.|.:: .|||||||::...:..  :||.|..|
Mouse   673 NVLPVSLAFDKCTACSPKVLDQYEREGFTFLAKVFNSSHSFLEDLTGLTLLHQETQAAEIWDMSD 737

  Fly   674 EE 675
            ||
Mouse   738 EE 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	289/715 (40%)
Atg7	NP_001240646.1	E1_like_apg7	54..740	CDD:273590	289/715 (40%)