Protein Alignment Atg7 and Mocs3

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_001153802.1
• Gene: Mocs3 / 69372
• MGIID: 1916622
• Length: 460
• Species: Mus musculus
• Alignment Length: 452
• Identity: 103/452 - (22%)
• Similarity: 156/452 - (34%)
• Gaps: 136/452 - (30%)

  Fly   296 MGPRMVCMRDSMDPAKLAENSVNLNLKLMKWRLVPDLNLE---IISQTKCLLFGAGTLGCAVARN 357
            :.||....||.:             |:..:..|:|:|.:.   .::....|:.|.|.|||.:|:.
Mouse    49 LAPRAALSRDEI-------------LRYSRQLLLPELGVRGQLRLAAAAVLVVGCGGLGCPLAQY 100

  Fly   358 LLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIP 422
            |.:.|...:.|:|...|..||..||.|  |.:|.|| ..||.:||..|:.:|.:.|...|
Mouse   101 LAAAGVGRLGLVDHDVVETSNLARQVL--HGEAQAG-ESKARSAAAALRRLNSAVECVAY----- 157

  Fly   423 MPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLP----TLLGAAKEKIVINAALG 483
              ...:.|.....          ||:.:||:....|:..:|:|.    .|.|   ..:|..:||.
Mouse   158 --PRALAEDWALD----------LVRGYDVVADCCDNVPTRYLVNDACVLAG---RPLVSASALR 207

  Fly   484 FDSYLVMRH----------------GTTRKEAGDDG------------QEIEGLKCING------ 514
            |:..:.:.|                ..|.....|.|            |.:|.||...|
Mouse   208 FEGQMTVYHHDGGPCYRCVFPRPPPPETVTNCADGGVLGAVPGVLGCAQALEVLKIAAGLGSSYS 272

  Fly   515 ------DQLGCYFCNDVTAPGNSLKDRTLD-----QQCTVTR-PGVSNIAASYAVELLVAL-LQH 566
                  |.||.:|..      ..|:.|..|     ||.|||| ........|.|.:...|| |..
Mouse   273 GSMLLFDGLGGHFRR------IRLRRRRPDCVVCGQQPTVTRLQDYEAFCGSSATDKCRALKLLC 331

  Fly   567 PRKELAPAYYAQ---SGRGRSEETEEKVPEGLLGI----------LPHSIRGMLCNYENILPATQ 618
            |.:.::...|.:   ||          .|..||.:          ||||:...|...|      :
Mouse   332 PEERISVTDYKRLLDSG----------APHVLLDVRPQVEVDICRLPHSLHIPLSQLE------R 380

  Fly   619 KFAQCIACSAAVLNEYKKEGHAFLF-----------KTFETAKFLEDLTGISEFKRLNSEII 669
            :.|..:....|.|.:.|:|....:.           .:.:..|.|:.||.:.|...|..:.|
Mouse   381 RDADSLKLLGAALRKGKQESQEGVALPVYVICKLGNDSQKAVKVLQSLTAVPELDSLTVQDI 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	103/452 (23%)
Mocs3	NP_001153802.1	PRK07411	56..460	CDD:180967	101/445 (23%)
		Interaction with NFS1. /evidence=ECO:0000250|UniProtKB:O95396	158..238		16/92 (17%)