Protein Alignment Atg7 and Uba5

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_079968.2
• Gene: Uba5 / 66663
• MGIID: 1913913
• Length: 403
• Species: Mus musculus
• Alignment Length: 257
• Identity: 50/257 - (19%)
• Similarity: 89/257 - (34%)
• Gaps: 57/257 - (22%)

  Fly   327 RLVPDLNLEIISQTKCL------LFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLY 385
            ||:....:.|:|..|.:      :.|.|.:|...|..|...|...:.|.|..||..:|..|....
Mouse    53 RLMALKRMGIVSDYKKIRTYAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQ 117

  Fly   386 THADAVAGNRMKATTAAQRLKEINPSA--ETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLV- 447
            .:...::    |...|...|:.|||..  |...|.:               .|.||.:.....:
Mouse   118 PYQAGLS----KVHAAEHTLRNINPDVLFEVHNYNI---------------TTVEHFEHFMNRIS 163

  Fly   448 -------QDHDVIFLLTDSRESRWLPTLLGAAKEKIVINAALGFDSYLVMRHGTTRKEAGDDGQE 505
                   |..|::....|:.|:|            :.||.|..       ..|.|..|:|.....
Mouse   164 NGGLEEGQPVDLVLSCVDNFEAR------------MAINTACN-------ELGQTWMESGVSENA 209

  Fly   506 IEG-LKCINGDQLGCYFCNDVTAPGNSLKDRTLDQQ--CTVTRPGVSNIAASYAVELLVALL 564
            :.| ::.:...:..|:.|.......:::.::||.::  |..:.|....:.|...|:.::..|
Mouse   210 VSGHIQLMIPGESACFACAPPLVVASNIDEKTLKREGVCAASLPTTMGVVAGILVQNVLKFL 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	50/257 (19%)
Uba5	NP_079968.2	ThiF_MoeB_HesA_family	50..293	CDD:238386	50/257 (19%)
		UFM1-interacting sequence (UIS). /evidence=ECO:0000250|UniProtKB:Q9GZZ9	333..345
		Linker. /evidence=ECO:0000250|UniProtKB:Q9GZZ9	346..376
		UFC1-binding sequence (UFC). /evidence=ECO:0000250|UniProtKB:Q9GZZ9	388..403