Protein Alignment Atg7 and Atg7

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: XP_008761461.1
• Gene: Atg7 / 312647
• RGDID: 1304817
• Length: 703
• Species: Rattus norvegicus
• Alignment Length: 706
• Identity: 289/706 - (40%)
• Similarity: 407/706 - (57%)
• Gaps: 91/706 - (12%)

  Fly     9 LQFAPWESFVSPTFWHKLAELKLDHDRLSDSKRSITGHYTNRNASG--CLLEVDYTAYNRMAKPP 71
            |||||:.|.:...|||:|.:.||:..||.::.:.|.|:|.|.:::|  ..|.::::|::..|..|
  Rat     9 LQFAPFNSALDVGFWHELTQKKLNEYRLDEAPKDIKGYYYNGDSAGLPTRLTLEFSAFDMSAPTP 73

  Fly    72 KFSHSAIGTIYNKNTIEEFKALDKLQLLADEGKELLADMCSGGALRDPSLLTRFFVLSFADLKCH 136
            .....|:||::|.||:|.||..||..||.....|:...:.||.||.:|.||.:|.:|:|||||.:
  Rat    74 ARCCPAMGTLHNTNTLEAFKTADKKLLLEQSANEIWEAIKSGAALENPMLLNKFLLLTFADLKKY 138

  Fly   137 SYYYWFAFPCPLTPTLKLQGAVQKLR-----DLPNSSSYIMALK-------------ALPTESQN 183
            .:||||.  |   |.|.|..::..:|     |...|...|.||:             |||
  Rat   139 HFYYWFC--C---PALCLPESIPLIRGPVGLDQRLSPKQIQALEHAYDDLCRTEGVTALP----- 193

  Fly   184 FFILYANVEKNIFEARSLSSLDDKNVEF-------CYFGFADPSEY-EHPAWIMRNYAAFLLQQC 240
             :.|:...:..:     |.||.....:|       ...|..||... :||.|.:||   ||:...
  Rat   194 -YFLFKYDDDTV-----LVSLLKHYSDFFQGQRTKLTVGVYDPCNLTQHPGWPLRN---FLVLAA 249

  Fly   241 PSFVG--KPLKFLGLRHNQQMNIDD---SLVWKVIQTEA-----CDLSQSENIKFVGWELNKNGK 295
            ..:.|  :.::.|..|........|   |::::|...|.     |.       |.||||.|:.|.
  Rat   250 HRWSGSFQSVEVLCFRDRTMQGARDVTHSIIFEVKLPEMAFSPDCP-------KAVGWEKNQKGG 307

  Fly   296 MGPRMVCMRDSMDPAKLAENSVNLNLKLMKWRLVPDLNLEIISQTKCLLFGAGTLGCAVARNLLS 360
            ||||||.:...|||.:|||:||:||||||.|||||.|:|:.:...||||.|||||||.|||.|:.
  Rat   308 MGPRMVNLSGCMDPKRLAESSVDLNLKLMCWRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMG 372

  Fly   361 WGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPG 425
            ||.:|:|.:|:.|:.:||||||.||...|.:.|.:.||..||:||::|.|....:|:.:.|||||
  Rat   373 WGVRHVTFVDNAKISYSNPVRQPLYEFEDCLGGGKPKALAAAERLQKIFPGVNASGFNMSIPMPG 437

  Fly   426 HTIGES--LLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLPTLLGAAKEKIVINAALGFDSYL 488
            |.:..|  .:.|.:..::.:|:|:..|||||||.|:||||||||::.|:|.|:|||||||||:::
  Rat   438 HPVNFSDVTMEQARRDVEQLEELIDSHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFV 502

  Fly   489 VMRHGTTR-KEAG-------------DDGQEIEGLKCINGDQLGCYFCNDVTAPGNSLKDRTLDQ 539
            |||||..: |:.|             |.|..:  ...|.|.:|||||||||.|||:|.:||||||
  Rat   503 VMRHGLKKPKQQGAGDLCPSHLVAPADLGSSL--FANIPGYKLGCYFCNDVVAPGDSTRDRTLDQ 565

  Fly   540 QCTVTRPGVSNIAASYAVELLVALLQHPRKELAPAYYAQSGRGRSEETEEKVPEGLLGILPHSIR 604
            ||||:|||::.||.:.||||:|::||||....|   .|.|...|..|     |...||::||.||
  Rat   566 QCTVSRPGLAVIAGALAVELMVSVLQHPEGGYA---IASSSDDRMNE-----PPTSLGLVPHQIR 622

  Fly   605 GMLCNYENILPATQKFAQCIACSAAVLNEYKKEGHAFLFKTFETA-KFLEDLTGIS 659
            |.|..::|:||.:..|.:|.|||:.||::|::||..||.|.|.:: .|||||||::
  Rat   623 GFLSRFDNVLPVSLAFDKCTACSSKVLDQYEQEGFTFLAKVFNSSHSFLEDLTGLT 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	287/704 (41%)
Atg7	XP_008761461.1	E1_like_apg7	11..688	CDD:273590	287/704 (41%)