DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atg7 and Uba2

DIOPT Version :9

Sequence 1:	NP_611350.1	Gene:	Atg7 / 37141	FlyBaseID:	FBgn0034366	Length:	684	Species:	Drosophila melanogaster
Sequence 2:	NP_001094049.1	Gene:	Uba2 / 308508	RGDID:	1312023	Length:	639	Species:	Rattus norvegicus

Alignment Length:	204	Identity:	49/204 - (24%)
Similarity:	79/204 - (38%)	Gaps:	43/204 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   335 EIISQTKCLLFGAGTLGCAVARNLLSWGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKAT 399
            |.:|..:.|:.|||.:||.:.:||:..||.||.|:|...:..||..||.|:.....   .|.||.
  Rat    13 EAVSGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHV---GRSKAQ 74

  Fly   400 TAAQRLKEINPSAETAGYVLEIPMPGHTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRW 464
            .|.:.:.:.:|.|....:...|..|.:.:                :..:...::....|:|.:|
  Rat    75 VAKESVLQFHPQANIEAHHDSIMNPDYNV----------------EFFRQFILVMNALDNRAAR- 122

  Fly   465 LPTLLGAAKEKIVINAALGFDSYLVMRHGTTRKEAGDDGQEIEGLKCINGDQLGCYFCN----DV 525
                      ..|....|..|..|: ..||    ||..||    :..|......||.|:    ..
  Rat   123 ----------NHVNRMCLAADVPLI-ESGT----AGYLGQ----VTTIKKGVTECYECHPKPTQR 168

  Fly   526 TAPGNSLKD 534
            |.||.::::
  Rat   169 TFPGCTIRN 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	ATG7_N	9..303	CDD:293029
		E1_like_apg7	11..682	CDD:273590	49/204 (24%)
		Apg7	341..658	CDD:238763	47/198 (24%)
Uba2	NP_001094049.1	ThiF	9..>175	CDD:279270	49/200 (25%)
		Uba2_SUMO	19..443	CDD:238766	47/198 (24%)
		UAE_UbL	451..537	CDD:291402
		UBA2_C	548..634	CDD:292812
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900