Protein Alignment Atg7 and MOCS3

DIOPT Version :10

• Sequence 1: NP_611350.1
• Gene: Atg7 / 37141
• FlyBaseID: FBgn0034366
• Length: 684
• Species: Drosophila melanogaster
• Sequence 2: NP_055299.1
• Gene: MOCS3 / 27304
• HGNCID: 15765
• Length: 460
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 72/300 - (24%)
• Similarity: 118/300 - (39%)
• Gaps: 79/300 - (26%)

  Fly   299 RMVCMRDSMDPAKLAENSVNLNLKLMKWRLVPDLNL--EIISQTKC-LLFGAGTLGCAVARNLLS 360
            |:|.:......|.|:.:.:   |:..:..::|:|.:  ::...|.| |:.|.|.|||.:|:.|.:
Human    42 RLVPVSPLPPKAALSRDEI---LRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAA 103

  Fly   361 WGFKHITLLDSGKVGFSNPVRQNLYTHADAVAGNRMKATTAAQRLKEINPSAETAGYVLEIPMPG 425
            .|...:.|:|...|..||..||.|  |.:|:|| :.||.:||..|:.:|.:.|...|.
Human   104 AGVGRLGLVDYDVVEMSNLARQVL--HGEALAG-QAKAFSAAASLRRLNSAVECVPYT------- 158

  Fly   426 HTIGESLLAQTKEHLKVIEKLVQDHDVIFLLTDSRESRWLP----TLLGAAKEKIVINAALGFDS 486
                ::|...|      ...||:.:||:...:|:..:|:|.    .|.|   ..:|..:||.|:.
Human   159 ----QALTPAT------ALDLVRRYDVVADCSDNVPTRYLVNDACVLAG---RPLVSASALRFEG 210

  Fly   487 YLVMRH----------------GTTRKEAGDDG------------QEIEGLKCING--------- 514
            .:.:.|                ..|.....|.|            |.:|.||...|
Human   211 QITVYHYDGGPCYRCIFPQPPPAETVTNCADGGVLGVVTGVLGCLQALEVLKIAAGLGPSYSGSL 275

  Fly   515 ---DQLGCYFCNDVTAPGNSLKDRTLDQQCTVTRPGVSNI 551
               |.|..:|      ....|:.|.||......||.|:::
Human   276 LLFDALRGHF------RSIRLRSRRLDCAACGERPTVTDL 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg7	NP_611350.1	E1_like_apg7	11..682	CDD:273590	72/299 (24%)
MOCS3	NP_055299.1	ThiF_MoeB_HesA_family	62..285	CDD:238386	59/245 (24%)
		Interaction with NFS1. /evidence=ECO:0000269|PubMed:23593335	158..238		17/99 (17%)
		RHOD_ThiF	327..460	CDD:238784