Protein Alignment CG5335 and LGALS8

DIOPT Version :10

• Sequence 1: NP_611349.2
• Gene: CG5335 / 37140
• FlyBaseID: FBgn0034365
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_006490.3
• Gene: LGALS8 / 3964
• HGNCID: 6569
• Length: 359
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 84/359 - (23%)
• Similarity: 132/359 - (36%)
• Gaps: 87/359 - (24%)

  Fly     5 FAGNLSHPLEFGHVLEVVAKTIDGAARFHINLCTAKSTVDPNADIGLRFSCYF-RNDVIVRNSRI 68
            |.|.:...|:.|.::.:.......|.||.::|... |::.|.||:...|:..| |...||.|:.|
Human    19 FVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNG-SSMKPRADVAFHFNPRFKRAGCIVCNTLI 82

  Fly    69 NGAWGEEESHVMDPNTLPNPIVSGEFFLVYILCCEDSFAISINSREFCRFRYRMPLGTIRALEIR 133
            |..||.||.      |...|....:.|.:.|:..:|.|.:::|.:....:.:|:....|..|.|.
Human    83 NEKWGREEI------TYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIY 141

  Fly   134 DQIQV--------------------------------------------IKQVDHRTVFPN---- 150
            .::.:                                            |.::..|||:..
Human   142 GKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLPSNRGGDISKIAPRTVYTKSKDS 206

  Fly   151 ------------PWPAVHASDYFKAFSNDQPILFSPGHVIVLTARCFENKKGQFIIKFMDSDTKR 203
                        |...|.....|.|..|..   ..||..:|:......|.| .|.:..:...:|.
Human   207 TVNHTLTCTKIPPMNYVSKRLPFAARLNTP---MGPGRTVVVKGEVNANAK-SFNVDLLAGKSKD 267

  Fly   204 EELHFSVRFDEKAVVRNSMNKNFEFGSEERH-GGFPFVFNQQFKLALAFTEREVLTAVDGYNFFS 267
            ..||.:.|.:.||.||||..:. .:|.|||: ..|||.....|::.:....||...||:|.:...
Human   268 IALHLNPRLNIKAFVRNSFLQE-SWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLE 331

  Fly   268 YTWRTPNAMMNLVGFK-VTSINGLVVQITGVDHL 300
            |..|          || ::||:.|  :|.|..||
Human   332 YKHR----------FKELSSIDTL--EINGDIHL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5335	NP_611349.2	Gal-bind_lectin	12..140	CDD:459768	33/172 (19%)
		GLECT	172..297	CDD:238025	37/126 (29%)
LGALS8	NP_006490.3	Gal-bind_lectin	24..149	CDD:214904	33/131 (25%)
		Gal-bind_lectin	236..356	CDD:214904	40/135 (30%)