DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5335 and Lgals9

DIOPT Version :9

Sequence 1:	NP_611349.2	Gene:	CG5335 / 37140	FlyBaseID:	FBgn0034365	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001375428.1	Gene:	Lgals9 / 25476	RGDID:	3005	Length:	354	Species:	Rattus norvegicus

Alignment Length:	372	Identity:	83/372 - (22%)
Similarity:	123/372 - (33%)	Gaps:	108/372 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FAGNLSHPLEFGHVLEVVAKTIDGAA-----RFHINLCTAKSTVDPNADIGLRFSCYF-RNDVIV 63
            |.|.:...|:.|  |::   |:.|..     |..:|..|..|    ..||...|:..| ....:|
  Rat    17 FTGIIQGGLQNG--LQI---TLQGTVHPFPNRIAVNFQTGFS----GNDIAFHFNPRFEEGGYVV 72

  Fly    64 RNSRINGAWGEEESHVMDPNTLPNPIVSGEFFLVYILCCEDSFAISINSREFCRFRYRMPLGTIR 128
            .|::.||.||.||      ..:..|...|..|.:..|.....|.:.:|...|.::.:|:|...:.
  Rat    73 CNTKQNGKWGPEE------RKMQMPFQKGMPFELCFLVQRSEFKVMVNKNFFVQYSHRVPYHLVD 131

  Fly   129 ALEIRDQIQV-IKQVDHRTVFPNPWPAVHASDYFKAFSNDQPIL--------------FSPGH-- 176
            .:.:...:.: .....:.|..|       ....|......||:.              |.|.|
  Rat   132 TISVSGCLHLSFINFQNSTAAP-------VQPVFSTMQFSQPVQFPRMPKGRKQRTQGFQPAHQA 189

  Fly   177 ----VIVLTARCFENKKGQ----------------FIIKFMDS-------------------DTK 202
                .|:.|....   .||                :.|.|..|                   |.|
  Rat   190 PVAQTIIHTVHSI---PGQMLSTPGIPPMAYPTPAYTIPFFTSIPNGFYPSKSINISGVVLPDAK 251

  Fly   203 REEL----------HFSVRFDEKAVVRNSMNKNFEFGSEERH--GGFPFVFNQQFKLALAFTERE 255
            |..:          |.:.||:||.||||:...| .:|.|||.  |..||...|.|.:.:......
  Rat   252 RFHINLRCGGDIAFHLNPRFNEKVVVRNTQINN-SWGPEERSLPGRMPFNRGQSFSVWILCEGHC 315

  Fly   256 VLTAVDGYNFFSYTWRTPNAMMNLVGFKVTSINGLVVQITGVDHLQT 302
            ...||||.:...|..|    :.||.......:.| .:|:|   |:||
  Rat   316 FKVAVDGQHICEYYHR----LKNLPDINTLEVAG-DIQLT---HVQT 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5335	NP_611349.2	Gal-bind_lectin	5..140	CDD:278752	32/141 (23%)
CG5335	NP_611349.2	GLECT	172..297	CDD:238025	43/177 (24%)
Lgals9	NP_001375428.1	Gal-bind_lectin	22..145	CDD:214904	30/137 (22%)
		Beta-galactoside binding 1. /evidence=ECO:0000250	81..87		4/11 (36%)
		Gal-bind_lectin	231..353	CDD:214904	34/130 (26%)
		Beta-galactoside binding 2. /evidence=ECO:0000250	286..292		3/5 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11346
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.020