DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5335 and lec-2

DIOPT Version :9

Sequence 1:	NP_611349.2	Gene:	CG5335 / 37140	FlyBaseID:	FBgn0034365	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001379091.1	Gene:	lec-2 / 174560	WormBaseID:	WBGene00002265	Length:	1245	Species:	Caenorhabditis elegans

Alignment Length:	313	Identity:	85/313 - (27%)
Similarity:	129/313 - (41%)	Gaps:	68/313 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FAGNLSHPLEFGHVLEVVAKTIDGAARFHINLCTAKSTVDPNADIGLRFSCYFRNDVIVRNSRIN 69
            :...|..|.|.|..|.|..||.:.:.||.:||.|..:....| |:.|..|..|....:|.|:...
Worm   978 YRSKLVEPFEPGQTLIVKGKTGEDSIRFTVNLHTNTADFSGN-DVPLHVSVRFDEGKLVFNTFSK 1041

  Fly    70 GAWGEEESHVMDPNTLPNPIVSGEFFLVYILCCEDSFAISINSREFCRFRYRMPLGTIRALEIRD 134
            |.||:||..       .||...|:...:.|...:..|.|.::.:|...:.:|:||.:|....|..
Worm  1042 GEWGKEERK-------SNPYKKGDDIDIRIRAHDSKFQIFVDQKEVKEYEHRVPLSSITHFTIDG 1099

  Fly   135 QIQVIKQVDHRTVFPNPWPAVHASDYFKAFSNDQPILFSPGHVIVLTARCF---ENKKGQFIIKF 196
            .:.|.........:|.|:.:..|.:.           .:||..:.:    |   |.|..:|.|..
Worm  1100 DVLVNYIHWGGKYYPVPYESGLAGEG-----------LAPGKTLTV----FGIPEKKAKRFHINL 1149

  Fly   197 MDSDTKRE---ELHFSVRFDEKAVVRNSMNKNFEFGSEERHGGFPF---------VFNQQFKLAL 249
            :    |:.   .||.:.|||||.|||||: .|..:|:|||.|..||         :.|:.:..|:
Worm  1150 L----KKNGDIALHLNARFDEKHVVRNSL-INSAWGNEEREGKMPFEKAVGFDLEIHNEPYAFAV 1209

  Fly   250 AFTEREVLTAVDGYNFFSYTWR-TPNAMMNLVGFKVTSINGLV----VQITGV 297
                     .|:|..|.||..| :|:           .:|||.    |:|||:
Worm  1210 ---------TVNGERFASYAHRLSPD-----------EVNGLQIGGDVEITGI 1242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5335	NP_611349.2	Gal-bind_lectin	5..140	CDD:278752	38/134 (28%)
CG5335	NP_611349.2	GLECT	172..297	CDD:238025	43/144 (30%)
lec-2	NP_001379091.1	rne	<136..298	CDD:236766
		PRK14949	<235..662	CDD:237863
		rne	<474..771	CDD:236766
		rne	<794..963	CDD:236766
		GLECT	978..1108	CDD:214596	38/137 (28%)
		GLECT	1116..1243	CDD:238025	46/167 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I6518
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	1	1.000	-	-		otm14067
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.020