DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5335 and lgals9

DIOPT Version :9

Sequence 1:	NP_611349.2	Gene:	CG5335 / 37140	FlyBaseID:	FBgn0034365	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_012808599.1	Gene:	lgals9 / 100145704	XenbaseID:	XB-GENE-5813327	Length:	446	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	64/285 - (22%)
Similarity:	114/285 - (40%)	Gaps:	40/285 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LTEFAGNLSHPLEFGHVLEVVAKTIDGAARFHIN-LCTAKSTVDPNADIGLRFSCYFRNDVIVRN 65
            |..|...:...|..|..|.:.....:...||.:| :|.       |.|:...|:..|..|.|..|
Frog    11 LMPFQSAIPGGLSEGKTLTIEGLVHNDCKRFAVNFICF-------NNDVAFHFNPRFDKDNIACN 68

  Fly    66 SRINGAWGEEE--SHVMDPNTLPNPIVSGEFFLVYILCCEDSFAISINSREFCRFRYRMPLGTIR 128
            ::::..||.||  .|::        ....|.|.:.|.....:|.:|:|......:|:|:....|:
Frog    69 TKLSNQWGLEERTDHML--------FGHNEAFEITITVLRSAFKVSVNGDHILEYRHRISYQGIQ 125

  Fly   129 ALEIRDQIQVIKQVDHRTVFPNPWPAVH---------ASDYFKAFSNDQPILFSPGHVIVLTARC 184
            :|::...|.:     ::..|.:|...:.         |.:|...|.:..|...|.|..:.:.. .
Frog   126 SLQLNGDITL-----NKVTFSDPPSQISTAPEKQLSVAPNYSIPFQSAIPGRISDGKTVTIEG-L 184

  Fly   185 FENKKGQFIIKFM--DSDTKREELHFSVRFDE-KAVVRNSMNKNFEFGSEERHGGFPFVFNQQFK 246
            ..:...:|.:.|:  ::||   ..||:.|||| ..:|.|:...| ::||.||....||..:..|:
Frog   185 VHSDCNRFTVNFLCFNNDT---AFHFNPRFDEDNTIVCNTKLDN-KWGSVERTQLMPFEKDDSFE 245

  Fly   247 LALAFTEREVLTAVDGYNFFSYTWR 271
            :.:...|.....:|:......|..|
Frog   246 IIIIIMEHVFQVSVNRKRILEYHHR 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5335	NP_611349.2	Gal-bind_lectin	5..140	CDD:278752	31/137 (23%)
CG5335	NP_611349.2	GLECT	172..297	CDD:238025	26/103 (25%)
lgals9	XP_012808599.1	GLECT	13..139	CDD:238025	31/145 (21%)
		GLECT	164..291	CDD:238025	28/112 (25%)
		Gal-bind_lectin	322..442	CDD:214904
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357844at33208
OrthoFinder	1	1.000	-	-		FOG0000178
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11346
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X133
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020