Protein Alignment Rgk2 and Rasd2

DIOPT Version :10

• Sequence 1: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_083458.1
• Gene: Rasd2 / 75141
• MGIID: 1922391
• Length: 266
• Species: Mus musculus
• Alignment Length: 192
• Identity: 48/192 - (25%)
• Similarity: 90/192 - (46%)
• Gaps: 28/192 - (14%)

  Fly   519 LDPPPPARYRVVMLGDAGVGKTALVNQFMTSEYMHTYDASLVLDDEFGEKTVSVLLDDEESDMVF 583
            |:.|....||:|:||.:.|||:::|::|:...:...|..::   ::|..|..::     ..||..
Mouse    12 LNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTI---EDFHRKVYNI-----HGDMYQ 68

  Fly   584 ID-------HPSVEMSVENSLSTYEPHGCVVVFSVVDRSSF----RVAEEIINY-LWQENYTKDK 636
            :|       ||...|   ..||.......::|||:..|.||    |:.::|:.. ...:|.||:.
Mouse    69 LDILDTSGNHPFPAM---RRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVKSCLKNKTKEA 130

  Fly   637 A---VILVGNKADLAR-ARLITSQEGKAL-AASRDAKFIETSSGIQHNVDELLVGILKQMRL 693
            |   :::.|||.|.:. .|.:.:.|.:.| :...:..:.|.|:....||:|:...:....:|
Mouse   131 AELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVNEMFYVLFSMAKL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	46/184 (25%)
Rasd2	NP_083458.1	Rhes_like	20..266	CDD:133343	46/184 (25%)
		Effector region	48..56		1/10 (10%)
		Interaction with GNB1, GNB2 and GNB3. /evidence=ECO:0000250	189..235		1/4 (25%)