Protein Alignment Rgk2 and RASL11A

DIOPT Version :10

• Sequence 1: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: NP_996563.1
• Gene: RASL11A / 387496
• HGNCID: 23802
• Length: 242
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 58/233 - (24%)
• Similarity: 105/233 - (45%)
• Gaps: 42/233 - (18%)

  Fly   509 LPATPDDSENLDPPPPARYRVVMLGDAGVGKTALVNQFMTSEYMHTYD-------ASLVLDDEFG 566
            |...|:.|.  |...|...::.:||...|||:|::.:|:|..::..|:       :.||..:  |
Human    12 LAPIPESSS--DYLLPKDIKLAVLGAGRVGKSAMIVRFLTKRFIGDYEPNTGKLYSRLVYVE--G 72

  Fly   567 EKTVSVLLDDEESDMVFIDH-PSVEMSVENSLSTYEPHGCVVVFSVVDRSSFRVAEEIINYLWQE 630
            :: :|:.:.|....:...|. |.|..|:...:...|  |.::|:|:.|..|:.....:..::.:.
Human    73 DQ-LSLQIQDTPGGVQIQDSLPQVVDSLSKCVQWAE--GFLLVYSITDYDSYLSIRPLYQHIRKV 134

  Fly   631 NYTKDKAVILVGNKADLARARLITSQEGKALAASRDAKFIETSSG---------IQHNVDEL--L 684
            :......||:||||.||..||.:.:|:|..||....:.|:|.|:.         .||...|:  :
Human   135 HPDSKAPVIIVGNKGDLLHARQVQTQDGIQLANELGSLFLEISTSENYEDVCDVFQHLCKEVSKM 199

  Fly   685 VGILKQMR---------------LKEKREKKATASKMK 707
            .|:..:.|               || :|.|:|.:.|:|
Human   200 HGLSGERRRASIIPRPRSPNMQDLK-RRFKQALSPKVK 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	53/215 (25%)
RASL11A	NP_996563.1	Small GTPase-like	17..241		56/228 (25%)
		RERG_RasL11_like	29..198	CDD:206713	44/173 (25%)