Protein Alignment Rgk2 and REM1

DIOPT Version :9

• Sequence 1: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Sequence 2: XP_005260461.1
• Gene: REM1 / 28954
• HGNCID: 15922
• Length: 306
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 104/289 - (35%)
• Similarity: 149/289 - (51%)
• Gaps: 41/289 - (14%)

  Fly   479 TSVNSTNSRASERSPFEGSCCGAGYANVDSLPATPDD--SENLDPPP--PARYRVVMLGDAGVGK 539
            ::|.||.|    :.|..|.............|| |||  ||:.|...  .|.||||:|||.||||
Human    34 STVPSTQS----QHPRLGQSASLNPPTQKPSPA-PDDWSSESSDSEGSWEALYRVVLLGDPGVGK 93

  Fly   540 TALVNQFMTSEYMHTY----DASL--VLDDEFGEKTVSVLLDDEESDMVFIDHPSVE-----MSV 593
            |:|.:.|...:....:    |.:|  |.:|.: |:|::|  |.|::.:|.:|....|     .|.
Human    94 TSLASLFAGKQERDLHEQLGDPALPSVAEDVY-ERTLTV--DGEDTTLVVVDTWEAEKLDKSWSQ 155

  Fly   594 ENSL---STYEPHGCVVVFSVVDRSSFRVAEEIINYLWQENYTKDKAVILVGNKADLARARLITS 655
            |:.|   |.|     |:|:|:.||.||..|.|:...|.:.:......:|||||||||||.|.::.
Human   156 ESCLQGGSAY-----VIVYSIADRGSFESASELRIQLRRTHQADHVPIILVGNKADLARCREVSV 215

  Fly   656 QEGKALAASRDAKFIETSSGIQHNVDELLVGILKQMRLKEKREKKATASKMKTSRTHISL-HLAK 719
            :||:|.|...|.||||||:.:||||.||..|:::|:||   |.:.:.|.:....|...|| ..|:
Human   216 EEGRACAVVFDCKFIETSATLQHNVAELFEGVVRQLRL---RRRDSAAKEPPAPRRPASLAQRAR 277

  Fly   720 ELLQKICLSDI------SKSKSCENLHVL 742
            ..|.::.....      ::||||.||.||
Human   278 RFLARLTARSARRRALKARSKSCHNLAVL 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	87/235 (37%)
		small_GTPase	527..694	CDD:197466	73/180 (41%)
REM1	XP_005260461.1	RGK	81..306	CDD:206715	87/235 (37%)
		small_GTPase	81..245	CDD:197466	70/171 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H7514
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D301527at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45775
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5084
SonicParanoid	1	1.000	-	-		X743
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.910