Protein Alignment Pepck1 and Pck1

DIOPT Version :10

• Sequence 1: NP_523784.2
• Gene: Pepck1 / 37131
• FlyBaseID: FBgn0003067
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_035174.1
• Gene: Pck1 / 18534
• MGIID: 97501
• Length: 622
• Species: Mus musculus
• Alignment Length: 638
• Identity: 400/638 - (62%)
• Similarity: 477/638 - (74%)
• Gaps: 27/638 - (4%)

  Fly    19 PQLHKLRQDNCGLYSHIRGIPIS----YGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENK 79
            ||||             .|:..|    .|::|.|...||.|||....||||:.:|||||||:|..
Mouse     3 PQLH-------------NGLDFSAKVIQGSLDSLPQAVRKFVEGNAQLCQPEYIHICDGSEEEYG 54

  Fly    80 VLIKSLLEAGTIVPLPKYDNCWLARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWIS 144
            .|:..:.|.|.|..|.||||||||.|:|.||||:||:|.|.|:.:.:|:|.|..|: ..||.|:|
Mouse    55 QLLAHMQEEGVIRKLKKYDNCWLALTDPRDVARIESKTVIITQEQRDTVPIPKTGL-SQLGRWMS 118

  Fly   145 PSDMDAAVQQRFPGCMKGRTMYVVPFSMGPVGSPLSKIGIELTDSAYVVASMRIMTRMGAAVLRQ 209
            ..|.:.|...|||||||||||||:||||||:||||:|||||||||.|||||||||||||.:||..
Mouse   119 EEDFEKAFNARFPGCMKGRTMYVIPFSMGPLGSPLAKIGIELTDSPYVVASMRIMTRMGISVLEA 183

  Fly   210 LAKKEEFVRALHSVGAPANGQVEQP---SWPCDPERTIILHKPAENLIVSYGSGYGGNSLLGKKC 271
            |. ..||::.|||||.|.  .:::|   :|.|:||.|:|.|.|....|:|:||||||||||||||
Mouse   184 LG-DGEFIKCLHSVGCPL--PLKKPLVNNWACNPELTLIAHLPDRREIISFGSGYGGNSLLGKKC 245

  Fly   272 FALRIGSTIAKQEGWLAEHMLILGITDPKGEKKYITAAFPSACGKTNLAMLNPSLANYKVECVGD 336
            |||||.|.:||:||||||||||||||:|:|:|||:.||||||||||||||:||||..:|||||||
Mouse   246 FALRIASRLAKEEGWLAEHMLILGITNPEGKKKYLAAAFPSACGKTNLAMMNPSLPGWKVECVGD 310

  Fly   337 DIAWMKFDSQGVLRAINPENGFFGVAPGTSMETNPIAMNTVFKNTIFTNVASTSDGGVFWEGMES 401
            ||||||||:||.||||||||||||||||||::|||.|:.|:.|||||||||.||||||:|||::.
Mouse   311 DIAWMKFDAQGNLRAINPENGFFGVAPGTSVKTNPNAIKTIQKNTIFTNVAETSDGGVYWEGIDE 375

  Fly   402 SLAPNVQITDWLGKPWTKDSGKPAAHPNSRFCTPAAQCPIIDEAWEDPAGVPISAMLFGGRRPAG 466
            .|||.|.||.|..|.|.....:|.|||||||||||:||||||.|||.|.||||..::||||||.|
Mouse   376 PLAPGVTITSWKNKEWRPQDAEPCAHPNSRFCTPASQCPIIDPAWESPEGVPIEGIIFGGRRPEG 440

  Fly   467 VPLIYEARDWTHGVFIGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSMEKR-- 529
            |||:|||..|.||||:|||||||||||||||||:|||||||||||||||||.|:||||||..|
Mouse   441 VPLVYEALSWQHGVFVGAAMRSEATAAAEHKGKIIMHDPFAMRPFFGYNFGKYLAHWLSMAHRPA 505

  Fly   530 GQVPKIFHVNWFRKSAEGKFMWPGYGENSRVLEWILRRVNGESCYVDSAIGHIPAEGALNLDGMK 594
            .::|||||||||||..:|||:|||:|||||||||:..|:.||.....:.||:||.|.||||.|:
Mouse   506 AKLPKIFHVNWFRKDKDGKFLWPGFGENSRVLEWMFGRIEGEDSAKLTPIGYIPKENALNLKGL- 569

  Fly   595 DKVDVKEIFSLPKEFWSQEVKDIRTYFESQVGADLPASIYQQLDELSSRVDNL 647
            ..|:|:|:|.:.||||.:||::|..|.|.||..|||..|.::|..|..|:..:
Mouse   570 GGVNVEELFGISKEFWEKEVEEIDRYLEDQVNTDLPYEIERELRALKQRISQM 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pepck1	NP_523784.2	PEPCK_GTP	52..640	CDD:238417	389/592 (66%)
Pck1	NP_035174.1	PEPCK_GTP	27..615	CDD:238417	389/592 (66%)
		Omega-loop. /evidence=ECO:0000250|UniProtKB:P07379	457..487		28/29 (97%)