Protein Alignment Pepck1 and pck-1

DIOPT Version :9

• Sequence 1: NP_523784.2
• Gene: Pepck1 / 37131
• FlyBaseID: FBgn0003067
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_497134.1
• Gene: pck-1 / 175171
• WormBaseID: WBGene00021043
• Length: 651
• Species: Caenorhabditis elegans
• Alignment Length: 643
• Identity: 340/643 - (52%)
• Similarity: 444/643 - (69%)
• Gaps: 33/643 - (5%)

  Fly    22 HKLRQDNCGLYSHIRGIPISYGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENKVLIKSLL 86
            |||..           |||..|:...|:..|:.||.|...|..|..::|||||::|...::..|:
 Worm    25 HKLNH-----------IPIFKGDFASLSPKVQRFVAEKAELMNPAGIYICDGSQKEYDDIVDKLV 78

  Fly    87 EAGTIVPLPKYDNCWLARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWISPSDMDAA 151
            |.|.:.||..|:|.:|.||:|.|||||||:|::.|:.:.:::....:||:..:|.|:|.......
 Worm    79 ERGVLTPLKAYENNYLCRTDPRDVARVESKTWMVTKDKYDSVCHTPDGVRPIMGQWMSEEQFGVE 143

  Fly   152 VQQRFPGCMKGRTMYVVPFSMGPVGSPLSKIGIELTDSAYVVASMRIMTRMGAAVLRQLAKKEEF 216
            :..||||||.||.|||||:||||:|.||||.|||||||.|||..||.|||||..||..|. ..:|
 Worm   144 LDSRFPGCMAGRPMYVVPYSMGPIGGPLSKNGIELTDSPYVVLCMRTMTRMGTKVLEALG-DNDF 207

  Fly   217 VRALHSVGAPANGQVEQP---SWPCDPERTIILHKPAENLIVSYGSGYGGNSLLGKKCFALRIGS 278
            ||.:||||.|.  .|:|.   .|||:||:.:|.|:|.|..|.|:||||||||:||||||||||..
 Worm   208 VRCIHSVGLPR--PVKQKVINHWPCNPEKVMIAHRPKEREIWSFGSGYGGNSILGKKCFALRIAC 270

  Fly   279 TIAKQEGWLAEHMLILGITDPKGEKKYITAAFPSACGKTNLAMLNPSLANYKVECVGDDIAWMKF 343
            .|.:.||||||||||:|:|:|:||:|:|.|||||||||||||||.|::..:||..||||||||||
 Worm   271 NIGRDEGWLAEHMLIMGVTNPEGEEKFIAAAFPSACGKTNLAMLTPTVPGWKVRVVGDDIAWMKF 335

  Fly   344 DSQGVLRAINPENGFFGVAPGTSMETNPIAMNTVFKNTIFTNVASTSDGGVFWEGMESSL----- 403
            .:.|.|.|||||.||||||||||.:||.:||.:...||||||||.|:||..||||:|..|
 Worm   336 GADGRLYAINPEAGFFGVAPGTSHKTNAMAMESCRANTIFTNVAETADGEYFWEGLEKELKEAKG 400

  Fly   404 -----APNVQITDWLGKPW-TKDSGKPAAHPNSRFCTPAAQCPIIDEAWEDPAGVPISAMLFGGR 462
                 ..:::||:|||:.| ..|.|| ||||||||..||.|||.|...||.|.||||.|::||||
 Worm   401 YTDEQLKHLEITNWLGERWHIGDEGK-AAHPNSRFTAPAKQCPNIHPDWEAPQGVPIDAIVFGGR 464

  Fly   463 RPAGVPLIYEARDWTHGVFIGAAMRSEATAAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSME 527
            ||.||||::|:..|.||:.:||.::||.|||||..||.:||||.|||||.|||:|.|:.||:.:.
 Worm   465 RPEGVPLVFESFSWEHGILVGALVKSETTAAAEFTGKNVMHDPMAMRPFMGYNYGKYLEHWIKLG 529

  Fly   528 KR-GQVPKIFHVNWFRKSAEGKFMWPGYGENSRVLEWILRRVNG--ESCYVDSAIGHIPAEGALN 589
            |. .:.||||||||||::.:.||:|||:|:|.|||:||||||.|  |...:::|||::|..|.:|
 Worm   530 KAPHKAPKIFHVNWFRETKDHKFLWPGFGDNIRVLDWILRRVAGGEEEIAIETAIGYVPKRGTIN 594

  Fly   590 LDGMKDKVDVKEIFSLPKEFWSQEVKDIRTYFESQVGADLPASIYQQLDELSSRVDNL 647
            |||: .::|..::.|:||::|.::|.:.|.:.::|||:|||..|..:||:|..||..|
 Worm   595 LDGL-PRIDWNDLMSIPKDYWVEDVDESRHFLDTQVGSDLPQPIRDELDKLEKRVHAL 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pepck1	NP_523784.2	PEPCK	54..644	CDD:279197	328/606 (54%)
pck-1	NP_497134.1	PEPCK_GTP	44..644	CDD:238417	328/604 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167288
Domainoid	1	1.000	466	1.000	Domainoid score	I223
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3356
Inparanoid	1	1.050	713	1.000	Inparanoid score	I333
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61114
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002991
OrthoInspector	1	1.000	-	-		mtm4840
orthoMCL	1	0.900	-	-		OOG6_102518
Panther	1	1.100	-	-	O	PTHR11561
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1986
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.900