Protein Alignment Pepck1 and pck-2

DIOPT Version :9

• Sequence 1: NP_523784.2
• Gene: Pepck1 / 37131
• FlyBaseID: FBgn0003067
• Length: 647
• Species: Drosophila melanogaster
• Sequence 2: NP_001366912.1
• Gene: pck-2 / 172556
• WormBaseID: WBGene00011232
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 618
• Identity: 345/618 - (55%)
• Similarity: 443/618 - (71%)
• Gaps: 14/618 - (2%)

  Fly    38 IPISYGNVDLLTTGVRAFVEEGIALCQPDQVHICDGSEQENKVLIKSLLEAGTIVPLPKYDNCWL 102
            :||..|:..||...|:.|:.|...|.:|..:.|||||:.|...||..|:|.|.:..|..|:|.::
 Worm    43 VPILKGDFHLLPAKVQRFIAEKAELMRPRGIFICDGSQHEADELIDKLIERGMLSKLEAYENNYI 107

  Fly   103 ARTNPADVARVESRTFICTERREETIPTPVEGVKGTLGNWISPSDMDAAVQQRFPGCMKGRTMYV 167
            .||:|.|||||||:|::.|:.:.:|:....|||:..:|:|::|.|:...:..||||||.||.|||
 Worm   108 CRTDPKDVARVESKTWMVTKNKYDTVTHTKEGVEPIMGHWLAPEDLATELDSRFPGCMAGRIMYV 172

  Fly   168 VPFSMGPVGSPLSKIGIELTDSAYVVASMRIMTRMGAAVLRQLAKKEEFVRALHSVGAPANGQVE 232
            :||||||||.|||||||:||||.|||.|||||||:...|...|. .::|||.:||||.|.  .|:
 Worm   173 IPFSMGPVGGPLSKIGIQLTDSNYVVLSMRIMTRVNNDVWDALG-NQDFVRCIHSVGLPR--PVK 234

  Fly   233 Q---PSWPCDPERTIILHKPAENLIVSYGSGYGGNSLLGKKCFALRIGSTIAKQEGWLAEHMLIL 294
            |   ..|||:|||.:|.|:|.|..|.|:|||||||||||||||||||.|.|||.|||:||||||:
 Worm   235 QRVINHWPCNPERVLIAHRPPEREIWSFGSGYGGNSLLGKKCFALRIASNIAKDEGWMAEHMLIM 299

  Fly   295 GITDPKGEKKYITAAFPSACGKTNLAMLNPSLANYKVECVGDDIAWMKFDSQGVLRAINPENGFF 359
            |:|.|.|.:.:|.|||||||||||||||.|:|..:||.|||||||||||...|.|.|||||.|||
 Worm   300 GVTRPCGREHFIAAAFPSACGKTNLAMLEPTLPGWKVRCVGDDIAWMKFGEDGRLYAINPEAGFF 364

  Fly   360 GVAPGTSMETNPIAMNTVFKNTIFTNVASTSDGGVFWEGMESSLA-PNVQITDWLGKPWTKDSGK 423
            |||||||.:|||:|:.|..||:||||||.|::|..||||:|..:| .||.||.|||:.|  ..|:
 Worm   365 GVAPGTSNKTNPMAVATFQKNSIFTNVAETANGEYFWEGLEDEIADKNVDITTWLGEKW--HIGE 427

  Fly   424 P--AAHPNSRFCTPAAQCPIIDEAWEDPAGVPISAMLFGGRRPAGVPLIYEARDWTHGVFIGAAM 486
            |  ||||||||..||.|||||...||.|.||||.|::||||||.|||||||...|.||||.|:.:
 Worm   428 PGVAAHPNSRFAAPANQCPIIHPDWESPQGVPIEAIIFGGRRPQGVPLIYETNSWEHGVFTGSCL 492

  Fly   487 RSEATAAAEHKGKVIMHDPFAMRPFFGYNFGDYVAHWLSMEKRG-QVPKIFHVNWFRKSAEGKFM 550
            :||||||||..||.:||||.|||||.|||||.|:.|||.::... ::|||:|||||||.:..||:
 Worm   493 KSEATAAAEFTGKTVMHDPMAMRPFMGYNFGKYLQHWLDLKTDSRKMPKIYHVNWFRKDSNNKFL 557

  Fly   551 WPGYGENSRVLEWILRRVNGE-SCYVDSAIGHIPAEGALNLDGMKDKVDVKEIFSLPKEFWSQEV 614
            |||:|:|.||::||:||::|| ...|::.||.:||:|::||:|: .:|:..|:.|:|.::|.|:.
 Worm   558 WPGFGDNIRVIDWIIRRLDGEQEIGVETPIGTVPAKGSINLEGL-GEVNWDELMSVPADYWKQDA 621

  Fly   615 KDIRTYFESQVGADLPASIYQQLDELSSRVDNL 647
            ::||.:.:.|||.|||..:..::|....||..|
 Worm   622 QEIRKFLDEQVGEDLPEPVRAEMDAQEKRVQTL 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pepck1	NP_523784.2	PEPCK	54..644	CDD:279197	336/597 (56%)
pck-2	NP_001366912.1	PEPCK_GTP	57..647	CDD:238417	337/595 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167287
Domainoid	1	1.000	466	1.000	Domainoid score	I223
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3356
Inparanoid	1	1.050	713	1.000	Inparanoid score	I333
Isobase	1	0.950	-	0	Normalized mean entropy	S2278
OMA	1	1.010	-	-		QHG61114
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002991
OrthoInspector	1	1.000	-	-		mtm4840
orthoMCL	1	0.900	-	-		OOG6_102518
Panther	1	1.100	-	-	LDO	PTHR11561
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1986
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.850