Protein Alignment Pepck2 and pck-2

DIOPT Version :9

• Sequence 1: NP_611341.1
• Gene: Pepck2 / 37130
• FlyBaseID: FBgn0034356
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: NP_001366912.1
• Gene: pck-2 / 172556
• WormBaseID: WBGene00011232
• Length: 654
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 344/609 - (56%)
• Similarity: 446/609 - (73%)
• Gaps: 12/609 - (1%)

  Fly    34 GDAKILTPAVKQYVEKCVELCQPERVHICDGTEVESKLLQGIMLKKGTIIPLPKYENCWLARTNP 98
            ||..:|...|::::.:..||.:|..:.||||::.|:..|...::::|.:..|..|||.::.||:|
 Worm    48 GDFHLLPAKVQRFIAEKAELMRPRGIFICDGSQHEADELIDKLIERGMLSKLEAYENNYICRTDP 112

  Fly    99 ADVARVEGKTFISTDSKEQTVPVTEKATPGMLGNWIAEKDMQAAIKERFPGCMKGRTMYVIPFSM 163
            .||||||.||::.|.:|..||..|::....::|:|:|.:|:...:..||||||.||.||||||||
 Worm   113 KDVARVESKTWMVTKNKYDTVTHTKEGVEPIMGHWLAPEDLATELDSRFPGCMAGRIMYVIPFSM 177

  Fly   164 GPVGSPLSKIGIEITDSPYVVESMKIMTRAGNPVLNYLQSGDGQFVKCLHSVGTPKSGVQ-AMPS 227
            ||||.|||||||::|||.|||.||:||||..|.|.:.|  |:..||:|:||||.|:...| .:..
 Worm   178 GPVGGPLSKIGIQLTDSNYVVLSMRIMTRVNNDVWDAL--GNQDFVRCIHSVGLPRPVKQRVINH 240

  Fly   228 WPCDPERTIVLHKPAENEIVSYGSGYGGNSLLGKKCLALRIGSTIAKREGWLAEHMLILGITNPQ 292
            |||:|||.::.|:|.|.||.|:||||||||||||||.||||.|.|||.|||:||||||:|:|.|.
 Worm   241 WPCNPERVLIAHRPPEREIWSFGSGYGGNSLLGKKCFALRIASNIAKDEGWMAEHMLIMGVTRPC 305

  Fly   293 GKKIYIAAAFPSACGKTNLAMMTPTLPGYKVECVGDDIAWMKFDNKGVLRAINPENGFFGVAPGT 357
            |::.:||||||||||||||||:.|||||:||.|||||||||||...|.|.|||||.|||||||||
 Worm   306 GREHFIAAAFPSACGKTNLAMLEPTLPGWKVRCVGDDIAWMKFGEDGRLYAINPEAGFFGVAPGT 370

  Fly   358 SRATNPIAMDTIFRNSVFTNVASTSDGGVYWEGMEKDQL--KGVTVTDWLGKLWSQESGKP--AA 418
            |..|||:|:.|..:||:|||||.|::|..:|||:| |::  |.|.:|.|||:.|  ..|:|  ||
 Worm   371 SNKTNPMAVATFQKNSIFTNVAETANGEYFWEGLE-DEIADKNVDITTWLGEKW--HIGEPGVAA 432

  Fly   419 HPNSRFCTPASQCPIIDPAWEDSEGVPISAILFGGRRPSGVPLVYEARDWKHGVFIGAAMRSEAT 483
            ||||||..||:|||||.|.||..:||||.||:||||||.||||:||...|:||||.|:.::||||
 Worm   433 HPNSRFAAPANQCPIIHPDWESPQGVPIEAIIFGGRRPQGVPLIYETNSWEHGVFTGSCLKSEAT 497

  Fly   484 AAAEFKGKVIMHDPFAMRPFFGYNFGDYLGHWLSME-QRGQVPKIFHVNWFRKSSEGKFLWPGFG 547
            |||||.||.:||||.|||||.|||||.||.|||.:: ...::|||:|||||||.|..||||||||
 Worm   498 AAAEFTGKTVMHDPMAMRPFMGYNFGKYLQHWLDLKTDSRKMPKIYHVNWFRKDSNNKFLWPGFG 562

  Fly   548 ENSRVLDWIFRRVEGEQ-CFEDSPIGRLPSKNSLNLDSLENIDLDQLFDLPKDFWEQEVAAIERY 611
            :|.||:|||.||::||| ...::|||.:|:|.|:||:.|..::.|:|..:|.|:|:|:...|.::
 Worm   563 DNIRVIDWIIRRLDGEQEIGVETPIGTVPAKGSINLEGLGEVNWDELMSVPADYWKQDAQEIRKF 627

  Fly   612 FEEQVGHHLPGAVAEELRELKARV 635
            .:||||..||..|..|:...:.||
 Worm   628 LDEQVGEDLPEPVRAEMDAQEKRV 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pepck2	NP_611341.1	PEPCK	45..635	CDD:279197	338/596 (57%)
pck-2	NP_001366912.1	PEPCK_GTP	57..647	CDD:238417	339/594 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167290
Domainoid	1	1.000	466	1.000	Domainoid score	I223
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	713	1.000	Inparanoid score	I333
Isobase	1	0.950	-	0	Normalized mean entropy	S2278
OMA	1	1.010	-	-		QHG61114
OrthoDB	1	1.010	-	-		D135245at33208
OrthoFinder	1	1.000	-	-		FOG0002991
OrthoInspector	1	1.000	-	-		mtm4840
orthoMCL	1	0.900	-	-		OOG6_102518
Panther	1	1.100	-	-	O	PTHR11561
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4022
SonicParanoid	1	1.000	-	-		X1986
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.890