Protein Alignment Pepck2 and AgaP_AGAP003350

DIOPT Version :9

• Sequence 1: NP_611341.1
• Gene: Pepck2 / 37130
• FlyBaseID: FBgn0034356
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_003436452.1
• Gene: AgaP_AGAP003350 / 1275028
• VectorBaseID: AGAP003350
• Length: 650
• Species: Anopheles gambiae
• Alignment Length: 612
• Identity: 425/612 - (69%)
• Similarity: 496/612 - (81%)
• Gaps: 8/612 - (1%)

  Fly    34 GDAKILTPAVKQYVEKCVELCQPERVHICDGTEVESKLLQGIMLKKGTIIPLPKYENCWLARTNP 98
            |:..:|:..|:::||:...:|||:|:||.||:|.||..|...:..:|||.|||||:|||||||||
Mosquito    40 GEVSLLSDKVRRFVEESAAMCQPDRIHIVDGSESESSTLLKTLHSQGTIKPLPKYDNCWLARTNP 104

  Fly    99 ADVARVEGKTFISTDSKEQTVPVTEKATPGMLGNWIAEKDMQAAIKERFPGCMKGRTMYVIPFSM 163
            |||||||.||||.|:..||.:|..:....|.|||||:..|...||..|||||||||||:|:||||
Mosquito   105 ADVARVESKTFICTERPEQAIPTPKPGVNGALGNWISPADYDRAIMSRFPGCMKGRTMFVVPFSM 169

  Fly   164 GPVGSPLSKIGIEITDSPYVVESMKIMTRAGNPVLNYLQSGDGQFVKCLHSVGTPKSGVQAMPSW 228
            ||:.|||||||||||||.|||.||:||||.|..||:.| |.:..|::||||||||.:|..|:|||
Mosquito   170 GPIASPLSKIGIEITDSAYVVASMRIMTRMGAEVLDKL-SDNSDFIRCLHSVGTPANGKIAVPSW 233

  Fly   229 PCDPERTIVLHKPAENEIVSYGSGYGGNSLLGKKCLALRIGSTIAKREGWLAEHMLILGITNPQG 293
            ||||||||:|||||.||||||||||||||||||||.|||||||||:|||||||||||||||:|.|
Mosquito   234 PCDPERTIILHKPANNEIVSYGSGYGGNSLLGKKCFALRIGSTIAQREGWLAEHMLILGITDPNG 298

  Fly   294 KKIYIAAAFPSACGKTNLAMMTPTLPGYKVECVGDDIAWMKFDNKGVLRAINPENGFFGVAPGTS 358
            .|.||||||||||||||||||.|||||||:|||||||||||||:||.||||||||||||||||||
Mosquito   299 VKKYIAAAFPSACGKTNLAMMNPTLPGYKIECVGDDIAWMKFDSKGQLRAINPENGFFGVAPGTS 363

  Fly   359 RATNPIAMDTIFRNSVFTNVASTSDGGVYWEGMEKDQLKGVTVTDWLGKLWS-QESGKPAAHPNS 422
            ..|||.||:||::|::||||||||||||:||||||:....|.:|||||..|. .||..|||||||
Mosquito   364 SETNPNAMETIYKNTIFTNVASTSDGGVFWEGMEKEVSSDVEITDWLGNPWKLGESKTPAAHPNS 428

  Fly   423 RFCTPASQCPIIDPAWEDSEGVPISAILFGGRRPSGVPLVYEARDWKHGVFIGAAMRSEATAAAE 487
            |||.||.|||||||||||||||||||||||||||.||||||||..|.||||:|::||||:|||||
Mosquito   429 RFCAPAGQCPIIDPAWEDSEGVPISAILFGGRRPQGVPLVYEANSWSHGVFVGSSMRSESTAAAE 493

  Fly   488 FKGKVIMHDPFAMRPFFGYNFGDYLGHWLSMEQR-----GQVPKIFHVNWFRKSSEGKFLWPGFG 547
            .|.||||:|||||||||||||||||.||||||||     |..|||||||||||.:.|||||||||
Mosquito   494 HKAKVIMNDPFAMRPFFGYNFGDYLKHWLSMEQRASAAGGHAPKIFHVNWFRKDANGKFLWPGFG 558

  Fly   548 ENSRVLDWIFRRVEGEQCFEDSPIGRLPSKNSLNLDSLEN-IDLDQLFDLPKDFWEQEVAAIERY 611
            ||||||:||..|::...|:.|:||||:|::.|||||.|.: ::..:||.:|||||.:||..:::|
Mosquito   559 ENSRVLEWILHRIDDADCYRDTPIGRVPTEGSLNLDGLSSPVNERELFSIPKDFWLREVEEVKQY 623

  Fly   612 FEEQVGHHLPGAVAEELRELKARVADM 638
            ::.|:...||..:|.||.:||:|:..|
Mosquito   624 YDNQLPQDLPAEIASELEQLKSRIEKM 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pepck2	NP_611341.1	PEPCK	45..635	CDD:279197	420/596 (70%)
AgaP_AGAP003350	XP_003436452.1	PEPCK	51..647	CDD:279197	420/596 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	575	1.000	Domainoid score	I787
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61114
OrthoDB	1	1.010	-	-		D135245at33208
OrthoFinder	1	1.000	-	-		FOG0002991
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11561
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1986
TreeFam	0	0.000	Not matched by this tool.
	7	7.030