Protein Alignment Pepck2 and Pepck1

DIOPT Version :10

• Sequence 1: NP_611341.1
• Gene: Pepck2 / 37130
• FlyBaseID: FBgn0034356
• Length: 638
• Species: Drosophila melanogaster
• Sequence 2: XP_003436452.2
• Gene: Pepck1 / 1275028
• VectorBaseID: AGAMI1_001042
• Length: 650
• Species: Anopheles gambiae
• Alignment Length: 612
• Identity: 425/612 - (69%)
• Similarity: 495/612 - (80%)
• Gaps: 8/612 - (1%)

  Fly    34 GDAKILTPAVKQYVEKCVELCQPERVHICDGTEVESKLLQGIMLKKGTIIPLPKYENCWLARTNP 98
            |:..:|:..|:::||:...:|||:|:||.||:|.||..|...:..:|||.|||||:|||||||||
Mosquito    40 GEVSLLSDKVRRFVEESAAMCQPDRIHIVDGSESESSTLLKTLHSQGTIKPLPKYDNCWLARTNP 104

  Fly    99 ADVARVEGKTFISTDSKEQTVPVTEKATPGMLGNWIAEKDMQAAIKERFPGCMKGRTMYVIPFSM 163
            |||||||.||||.|:..||.:|..:....|.|||||:..|...||..|||||||||||:|:||||
Mosquito   105 ADVARVESKTFICTERPEQAIPTPKPGVNGALGNWISPADYDRAIMSRFPGCMKGRTMFVVPFSM 169

  Fly   164 GPVGSPLSKIGIEITDSPYVVESMKIMTRAGNPVLNYLQSGDGQFVKCLHSVGTPKSGVQAMPSW 228
            ||:.|||||||||||||.|||.||:||||.|..||:.| |.:..|::||||||||.:|..|:|||
Mosquito   170 GPIASPLSKIGIEITDSAYVVASMRIMTRMGAEVLDKL-SDNSDFIRCLHSVGTPANGKIAVPSW 233

  Fly   229 PCDPERTIVLHKPAENEIVSYGSGYGGNSLLGKKCLALRIGSTIAKREGWLAEHMLILGITNPQG 293
            ||||||||:|||||.||||||||||||||||||||.|||||||||:|||||||||||||||:|.|
Mosquito   234 PCDPERTIILHKPANNEIVSYGSGYGGNSLLGKKCFALRIGSTIAQREGWLAEHMLILGITDPNG 298

  Fly   294 KKIYIAAAFPSACGKTNLAMMTPTLPGYKVECVGDDIAWMKFDNKGVLRAINPENGFFGVAPGTS 358
            .|.||||||||||||||||||.|||||||:|||||||||||||:||.||||||||||||||||||
Mosquito   299 VKKYIAAAFPSACGKTNLAMMNPTLPGYKIECVGDDIAWMKFDSKGQLRAINPENGFFGVAPGTS 363

  Fly   359 RATNPIAMDTIFRNSVFTNVASTSDGGVYWEGMEKDQLKGVTVTDWLGKLWS-QESGKPAAHPNS 422
            ..|||.||:||::|::||||||||||||:||||||:....|.:|||||..|. .||..|||||||
Mosquito   364 SETNPNAMETIYKNTIFTNVASTSDGGVFWEGMEKEVSSDVEITDWLGNPWKLGESKTPAAHPNS 428

  Fly   423 RFCTPASQCPIIDPAWEDSEGVPISAILFGGRRPSGVPLVYEARDWKHGVFIGAAMRSEATAAAE 487
            |||.||.|||||||||||||||||||||||||||.||||||||..|.||||:|::||||:|||||
Mosquito   429 RFCAPAGQCPIIDPAWEDSEGVPISAILFGGRRPQGVPLVYEANSWSHGVFVGSSMRSESTAAAE 493

  Fly   488 FKGKVIMHDPFAMRPFFGYNFGDYLGHWLSMEQR-----GQVPKIFHVNWFRKSSEGKFLWPGFG 547
            .|.||||:|||||||||||||||||.||||||||     |..|||||||||||.:.|||||||||
Mosquito   494 HKAKVIMNDPFAMRPFFGYNFGDYLKHWLSMEQRASAAGGHAPKIFHVNWFRKDANGKFLWPGFG 558

  Fly   548 ENSRVLDWIFRRVEGEQCFEDSPIGRLPSKNSLNLDSLEN-IDLDQLFDLPKDFWEQEVAAIERY 611
            ||||||:||..|::...|:.|:||||:|::.|||||.|.: ::..:||.:|||||.:||..:::|
Mosquito   559 ENSRVLEWILHRIDDADCYRDTPIGRVPTEGSLNLDGLSSPVNERELFSIPKDFWLREVEEVKQY 623

  Fly   612 FEEQVGHHLPGAVAEELRELKARVADM 638
            ::.|:...||..:|.||.:||.|:..|
Mosquito   624 YDNQLPQDLPAEIASELEQLKIRIEKM 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pepck2	NP_611341.1	PEPCK_GTP	43..631	CDD:238417	419/594 (71%)
Pepck1	XP_003436452.2	None