Protein Alignment CG43066 and Slc6a21

DIOPT Version :10

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001028348.2
• Gene: Slc6a21 / 76713
• MGIID: 1923963
• Length: 749
• Species: Mus musculus
• Alignment Length: 575
• Identity: 176/575 - (30%)
• Similarity: 303/575 - (52%)
• Gaps: 30/575 - (5%)

  Fly    61 KMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALG 125
            |.:..|.::.:|:|||:.|||||||.|||||:||:.:.::|:|.||||..:|:.|||.:|:..:.
Mouse    54 KTENILILVAFSIGLGSTWRFPYLCHQNGGGSFLLMYFILLLLLGIPLMYMEMVIGQWLRMDNIQ 118

  Fly   126 VWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCPL--NGTGFELEEC 188
            .|..:.|||.|:|.|:.:..:.|.||.:.:::|..|||..||.|||||.:|||  |.:......|
Mouse   119 AWKYLVPWLSGVGYSNILACVLVVLYNSALVSWSLFYLGQSFDYPLPWQNCPLVENLSMVAGNTC 183

  Fly   189 AKSSETTYFWYRTTLDAAPSMDEPGGLKWWIV---LCLMLSWTIVFFIVMKGIQSSGKVVYFTSL 250
            ..|....||||.|.|.|:..|:|  |::..::   |||..:|..::..::..|:.|..::.|:.|
Mouse   184 LWSEPHQYFWYHTLLQASNQMEE--GIEVLVLNVTLCLFATWIFLYVTMVTRIKISVLMMIFSIL 246

  Fly   251 FPYIVLTIFFIRGITLRGA-GAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSY 314
            |..::|..||||.:.|.|: .|.|..:.|.::..|.....|..|...|.||.||..|::|.|.:|
Mouse   247 FSNVLLLCFFIRTLFLNGSVRASLWRLVTIELSILSSLDAWRQAGGHVLYSLGLGMGTIITFSTY 311

  Fly   315 NTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVDRCV---ASNTEILVKNKLL---- 372
            .....|.::....|::.|..|::.:|.|||.::||..|.:...|:   .||...|:.|.:|
Mouse   312 QPRGENYIKWASFVAMVNLATSLLSSFVIFLVMGFWTTTSGTMCIKRSVSNLINLIANGVLPKAA 376

  Fly   373 ----------GLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVEL 427
                      .|.......|..:.|. ::::. |...||:..:.:...||.||:::.|:|||...
Mouse   377 WPPGDIIHKPPLEYLAWINQLPNNLK-SQVIH-QTLPCSILIQKEKIMEGPGLSYVAFSQAISLF 439

  Fly   428 PGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFDIDIIKRVKKQHVTGV-VCLFCFIVGFIFCT 491
            ||:.|||::||..|..:|||:.:.:|||::..| ...|....|..::..| |||..|:...:|.:
Mouse   440 PGSSFWAIIFFMSLAIMGLGTMLTLLEGIVLPL-QKSISTFAKHPNLVQVLVCLGGFLGSLVFSS 503

  Fly   492 GAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIG-P 555
            ..|.|.:.:||.....:.|:::.:::.:::.::||.:||..::|...|......:.:.|.|:. |
Mouse   504 RPGSYVVFLFDDLLVPMVLIIIVVIQNLSLAWLYGIKRFRAEVFGQLGSLVWSPFTFLWSYVTLP 568

  Fly   556 VIMVCILVSSVVFMVIRNPTYGAWNADLGMIEQKSYPNWVMGIALSMILAGVLPM 610
            .::|.:.:..:......:|.|.:||..:....::.|....:|....:.:..:||:
Mouse   569 TLLVLLTIYFLNLYYSGSPYYVSWNDSMSHEVKQPYKKIPLGWVTFLSVLALLPI 623

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	176/575 (31%)
Slc6a21	NP_001028348.2	SLC5-6-like_sbd	48..622	CDD:444915	174/572 (30%)