Protein Alignment CG43066 and slc6a4a

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001035061.1
• Gene: slc6a4a / 664719
• ZFINID: ZDB-GENE-060314-1
• Length: 646
• Species: Danio rerio
• Alignment Length: 659
• Identity: 219/659 - (33%)
• Similarity: 337/659 - (51%)
• Gaps: 104/659 - (15%)

  Fly     5 KIIDAPRNGH---EMAPLNTRARGDGTHGVT--IVLTAPQR------NSVQSVDIPGN------- 51
            |:.::..||.   :..|...:..|.|...|:  ...|:||.      .....|:.||.
Zfish    19 KVPESQENGRLVVDSVPEKDQKSGSGPGQVSNGYRSTSPQSPKEGAGTGTDRVNTPGTFRTLVVQ 83

  Fly    52 ----EPERAAWSGKMQFFLSIIGYSVGLGNIWRFPYLCQQNGGGAFLIPFMVMLILEGIPLFLIE 112
                :|.|..||.||.|.||:|||:|.|||:|||||:|.||||||||:|:::|.:..|:|||.:|
Zfish    84 QTSLDPPRETWSKKMDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYLLMAVFGGVPLFYME 148

  Fly   113 LGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFVALYYNVIITWVFFYLFNSFRYPLPWSSCP 177
            |.:||..|.|.:.:|..:.|...|||.:.||:.|::|.|||.|:.|..:||.:|||..|||::|
Zfish   149 LALGQFHRSGCISIWKHVCPIFKGIGFAICIIALYIAFYYNTIMAWALYYLLSSFRATLPWTTC- 212

  Fly   178 LNGTGFELEECAK--SSETTYFWYRTTLDAA--------------PSMDEPGGLKWWIVLCLMLS 226
              ...:....|..  |::....|...::..|              |.:.:.|.:.|.:.|||:..
Zfish   213 --NNRWNTPNCTHYLSTDLNVSWTNNSISPAEEFYVRQVLQVHLSPGLHQLGWVSWQLALCLLFI 275

  Fly   227 WTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFIRGITLRGAGAGLMHMYTPKVEKLLEPTVWL 291
            :|:|:|.:.||:::|||||:.|:.|||:||.|..|||.||.||..|::....|..:|||..||||
Zfish   276 FTVVYFSIWKGVKTSGKVVWVTATFPYLVLLILLIRGATLPGAWRGVVFYLKPDWKKLLTTTVWL 340

  Fly   292 DAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVLLVSVCNAVTAIYASVVIFAILGFKATVNVD 356
            |||.|:|:|.|..||.|:||.|||...|||.:|.|:.|..|.:|:..:..|||.:||:.|.:.
Zfish   341 DAAAQIFFSLGPGFGVLLAFASYNPFHNNCYKDALITSSVNCLTSFLSGFVIFTVLGYMAEMR-- 403

  Fly   357 RCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTELLRLQLSECSLAHELDNAAEGTGLAFIVFT 421
                                .||.|                   ::|.:     .|..|.||::.
Zfish   404 --------------------QQGVE-------------------TVAKD-----AGPSLLFIIYA 424

  Fly   422 QAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGMLCTLFD--IDIIKRVKKQHVTGVVCLFCFI 484
            :||..:|.|.|:|::||.|::.|||.|....|||::..:.|  ..::.|.::..|.|:||: |::
Zfish   425 EAIANMPAATFFAIIFFLMIIMLGLDSTFAGLEGVITAMLDEFPHLLARRREWFVLGLVCV-CYL 488

  Fly   485 VGFIFCTGAGEYWLKMFDSFAGTIGLVVVALMEMIAVIFIYGHERFTEDIFQMTGYRPGRYWQWT 549
            ......|..|.:.:|:|:.:|....::.|..:|:|||.:.||..||..|:..|.|:.||.:|:..
Zfish   489 GALSTLTYGGAFVVKLFEEYATGPAVITVVFLEVIAVSWFYGTTRFCNDVQLMLGFAPGLFWRVC 553

  Fly   550 WRYIGPVIMVCILVSSVVF---MVIRNPTYGAWNADLG-MIEQKSY---PNWVM-------GIAL 600
            |..|.|..::.|:||.:.|   :.:.:..|..|...|| .|...|:   |::::       |...
Zfish   554 WIAICPCFLLFIIVSFLAFPPEVKLFDYLYPFWTTVLGYCIGVSSFICVPSYMVYHLVTTKGTFQ 618

  Fly   601 SMILAGVLP 609
            ..:|.|:.|
Zfish   619 QRLLKGITP 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	205/587 (35%)
slc6a4a	NP_001035061.1	SLC5-6-like_sbd	91..628	CDD:294310	205/587 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810