Protein Alignment CG43066 and SLC6A13

DIOPT Version :9

• Sequence 1: NP_001246408.1
• Gene: CG43066 / 37129
• FlyBaseID: FBgn0262476
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 640
• Identity: 215/640 - (33%)
• Similarity: 324/640 - (50%)
• Gaps: 98/640 - (15%)

  Fly    19 LNTRARGDGTHGVTIVLTAPQRNSVQSVDIPGNEPERAAWSGKMQFFLSIIGYSVGLGNIWRFPY 83
            :::|..|..::|.    |.|....::..:..|. .||..|:.||:|.||:.|..:||||:|||||
Human     1 MDSRVSGTTSNGE----TKPVYPVMEKKEEDGT-LERGHWNNKMEFVLSVAGEIIGLGNVWRFPY 60

  Fly    84 LCQQNGGGAFLIPFMVMLILEGIPLFLIELGIGQRMRLGALGVWNTIHPWLGGIGISSCIVTLFV 148
            ||.:||||||.||::|.|...|||:||:|..:||....|.:..|..|.|...|||.:|.::.:.:
Human    61 LCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILL 125

  Fly   149 ALYYNVIITWVFFYLFNSFRYPLPWSSC-----------------PLNGTGFELEECAKSSETTY 196
            .:||.:::.|..||||:||...|||..|                 .||||    .|.| :|....
Human   126 NVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGT----SENA-TSPVIE 185

  Fly   197 FWYRTTLDAAPSMDEPGGLKWWIVLCLMLSWTIVFFIVMKGIQSSGKVVYFTSLFPYIVLTIFFI 261
            ||.|..|..:..:...|.|:|.:.|||:|:|.|.:|.:.||::|:|||||||:.|||::|.:..|
Human   186 FWERRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLI 250

  Fly   262 RGITLRGAGAGLMHMYTPKVEKLLEPTVWLDAATQVFYSFGLAFGSLIAFGSYNTPKNNCVRDVL 326
            ||:||.||..|:.....|.:.:|.:|.||:||.||:|:||.:..|.|.|.||||...|||.||.:
Human   251 RGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCI 315

  Fly   327 LVSVCNAVTAIYASVVIFAILGFKATVNVDRCVASNTEILVKNKLLGLNDTQGYEQAMSLLNGTE 391
            .:...|:.|:..|...||:||||                        ::..||
Human   316 ALCFLNSGTSFVAGFAIFSILGF------------------------MSQEQG------------ 344

  Fly   392 LLRLQLSECSLAHELDNAAEGTGLAFIVFTQAIVELPGAPFWAVLFFTMLLSLGLGSQIGILEGM 456
               :.:||.        |..|.|||||.:.:|:|.||.:|.||..||.|::.|||.||...:|.:
Human   345 ---VPISEV--------AESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESL 398

  Fly   457 LCTLFDI--DIIKRVKKQHVTGV-VCLFCFIVGFIFCTGAGEYWLKMFDSFAGT-IGLVVVALME 517
            :..|.|:  .:.::..::.|..: |.:..|:||.|..|..|.|..::||.:|.: :.|:.||:.|
Human   399 VTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFE 463

  Fly   518 MIAVIFIYGHERFTEDIFQMTGYRPGRYWQWTWRYIGPVIMVCILVSSVV----FMVIRNPTYGA 578
            .:.|.::||.:||.::|..|.||||....::.|.::.|.:.....:.|::    ....:..||..
Human   464 SLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPW 528

  Fly   579 WNADLGMIEQKSYPNWVMGI-------ALSMILAGVLPMPIVFLMRSFQCLKVDL 626
            |...||         |::.:       |.|:...|.|..|....:|...|...||
Human   529 WGDALG---------WLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDL 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43066	NP_001246408.1	SLC6sbd-B0AT-like	55..617	CDD:271364	204/593 (34%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		5/24 (21%)
		SLC6sbd_GAT2	32..575	CDD:271396	208/604 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810